Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916986 | 0.91 | ALDH1A1 (0.46) | ALDH1A1GAAPKMMRGPRX4LMNA | |
| SCHEMBL7911558 | 0.90 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1GAAPKMITGB3 | |
| SCHEMBL7903219 | 0.90 | LMNA (0.38) | L3MBTL1ALDH1A1GAAPKMITGB3 | |
| SCHEMBL7916990 | 0.89 | LMNA (0.41) | L3MBTL1ITGB3ITGA2BNPC1POLB | |
| SCHEMBL7910597 | 0.89 | ALDH1A1 (0.36) | L3MBTL1ALDH1A1GAAPKMITGB3 | |
| Hydrochloric Acid SCHEMBL7911590 | 0.87 | ITGB3 (0.37) | L3MBTL1ITGB3ITGA2BNPC1POLB | |
| SCHEMBL7911574 | 0.83 | LMNA (0.43) | ALDH1A1GAAPKMNPC1RAB9A | |
| SCHEMBL7910547 | 0.83 | HSD17B10 (0.38) | L3MBTL1ALDH1A1GAAPKMNPC1 | |
| SCHEMBL7911564 | 0.82 | SIRT2 (0.40) | LMNASMN1; SMN2NPSR1MAOBKDM4E | |
| SCHEMBL7911545 | 0.81 | CCNA2 (0.38) | ALDH1A1LMNASMN1; SMN2NPSR1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291485-B1 | TREATMENT OF POST-PTCA RESTENOSIS | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-1002797-A1 | 4,5-DIHYDRO- 1H]-BENZ g]INDAZOLE-3-CARBOXYLIC ACID DERIVATIVES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2000-05-24 | — | — | EP | disclosed |