Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | EDNRB | P24530 | 2/20 | 0.50 |
| ▸ | EDNRA | P25101 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910955 | 0.89 | MAOB (0.66) | MAOBRAB9ANPC1KMT2AMAOA | |
| SCHEMBL28628885 | 0.87 | KMT2A (0.62) | RAB9ANPC1KMT2AKDM4EMEN1 | |
| SCHEMBL7911107 | 0.85 | RAB9A (0.63) | MAOBRAB9ANPC1KMT2AKDM4E | |
| SCHEMBL3962253 | 0.85 | MAOB (0.61) | MAOBRAB9ANPC1KMT2AKDM4E | |
| SCHEMBL7907439 | 0.83 | MAOB (0.56) | MAOBRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL7908641 | 0.82 | ALOX5 (0.55) | MAOBNPC1MAOA | |
| SCHEMBL7910948 | 0.81 | MAOB (0.57) | MAOBRAB9ANPC1KMT2AKDM4E | |
| SCHEMBL7911112 | 0.81 | MAOB (0.57) | MAOBRAB9ANPC1KMT2AKDM4E | |
| SCHEMBL7910894 | 0.81 | FFAR4 (0.65) | MAOBKMT2AMAOAL3MBTL1LMNA | |
| SCHEMBL3191667 | 0.80 | MAOB (0.58) | MAOBRAB9ANPC1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |