Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28551096 | 0.95 | ALDH1A1 (0.60) | ALDH1A1MAPTNPC1HTTRAB9A | |
| SCHEMBL12207815 | 0.87 | CASP3 (0.49) | ALDH1A1MAPTNPC1HTTRAB9A | |
| SCHEMBL11443601 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTNPC1HTTRAB9A | |
| SCHEMBL11443209 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPTNPC1HTTRAB9A | |
| SCHEMBL12391039 | 0.80 | ASIC3 (0.50) | ALDH1A1MAPTNPC1HTTRAB9A | |
| SCHEMBL845167 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAPTNPC1HTTRAB9A | |
| SCHEMBL28551095 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPTNPC1HTTRAB9A | |
| SCHEMBL14664048 | 0.78 | CASP3 (0.63) | ALDH1A1MAPTCASP3SENP8SENP7 | |
| SCHEMBL28832082 | 0.78 | CASP3 (0.47) | ALDH1A1MAPTNPC1HTTRAB9A | |
| SCHEMBL28924864 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPTNPC1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330839-A | Method for preparing p-aminophenylacetylene | 金泰旭化学技术(无锡)有限公司 | 2025-01-21 | — | — | CN | claimed |
| US-4204078-A | REACTING NITROBROMOBENZENE WITH A HYDROXY-ACETYLENE COMPOUND; AMINE SOLVENT AND PALLADIUM COMPLEX CATALYST | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1980-05-20 | — | — | US | claimed |
| US-4128588-A | PALLADIUM-PHOSPHINE COMPLEX CATALYST | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1978-12-05 | — | — | US | claimed |
| US-20250391519-A1 | CHEMICAL SYNTHESIS PLATFORM | UNIV GLASGOW COURT (GB) | 2025-12-25 | — | — | US | disclosed |
| EP-4548355-A1 | CHEMICAL SYNTHESIS PLATFORM | The University Court Of The University Of Glasgow (GB) | 2025-05-07 | — | — | EP | disclosed |
| CN-119330839-A | Method for preparing p-aminophenylacetylene | 金泰旭化学技术(无锡)有限公司 | 2025-01-21 | — | — | CN | disclosed |
| CN-119330839-A | Method for preparing p-aminophenylacetylene | 金泰旭化学技术(无锡)有限公司 | 2025-01-21 | — | — | CN | disclosed |
| WO-2024003151-A1 | CHEMICAL SYNTHESIS PLATFORM | THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) | 2024-01-04 | — | — | WO | disclosed |
| WO-2023048034-A1 | METHOD FOR PRODUCING AROMATIC COMPOUND HAVING ETHYNYL GROUP | 東レ・ファインケミカル株式会社 | 2023-03-30 | — | — | WO | disclosed |
| WO-2023008401-A1 | METHOD FOR PRODUCING AROMATIC COMPOUND HAVING ETHYNYL GROUP | 東レ・ファインケミカル株式会社 | 2023-02-02 | — | — | WO | disclosed |
| US-6225499-B1 | REACTING N-ARYLMETHYLIDENE AMINOARYLBROMIDE WITH TERMINAL ACETYLENE IN PRESENCE OF BASE AND CATALYST SYSTEM COMPRISING PALLADIUM CATALYST AND CUPROUS SALT TO PRODUCE N-ARYLMETHYLIDENE AMINOARYLACETYLENE | CATALYTICA PHARMACEUTICALS, INC. | 2001-05-01 | — | — | US | disclosed |
| US-6100429-A | N-benzylidene aminophenylacetylene carbinols | CATALYTICA PHARMACEUTICALS, INC. (US) | 2000-08-08 | — | — | US | disclosed |
| EP-1019359-A2 | PROCESS FOR PREPARING AMINOARYLACETYLENES | Catalytica Pharmaceuticals, Inc. (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999003803-A2 | PROCESS FOR PREPARING AMINOARYLACETYLENES | CATALYTICA PHARMACEUTICALS, INC. (US) | 1999-01-28 | — | — | WO | disclosed |
| US-4219679-A | HIGH CONVERSION | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1980-08-26 | — | — | US | disclosed |
| US-4216341-A | Selective hydrogenation of certain nitroaromatic hydroxy substituted acetylenes over a heterogeneous RuS2 catalyst | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1980-08-05 | — | — | US | disclosed |
| US-4139561-A | RUTHENIUM HYDROGENATION CATALYST | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1979-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250391519-A1 | CHEMICAL SYNTHESIS PLATFORM | SET, CBS, COASY | ALDH1A1 2847/4885MAPT 2536/4885NPC1 849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.