Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 3/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913223 | 0.87 | ACHE (0.44) | ALDH1A1SMN1; SMN2KDM4ETSHRHSD17B10 | |
| SCHEMBL7916778 | 0.84 | SLC9A1 (0.33) | ALDH1A1SLC9A1KDM4ECYP1A2HPGD | |
| SCHEMBL7902801 | 0.75 | SLC9A1 (0.39) | ALDH1A1MAPTLMNASMN1; SMN2SLC9A1 | |
| SCHEMBL30640167 | 0.75 | KDM4E (0.32) | KDM4ETSHR | |
| SCHEMBL29108256 | 0.75 | KDM4E (0.32) | KDM4ETSHR | |
| SCHEMBL30640083 | 0.69 | MAPT (0.32) | ALDH1A1MAPTSMN1; SMN2TP53MAPK1 | |
| SCHEMBL29108328 | 0.69 | MAPT (0.32) | ALDH1A1MAPTSMN1; SMN2TP53MAPK1 | |
| SCHEMBL14029671 | 0.68 | KDM4C (0.45) | ALDH1A1MAPTHTTKDM4ETSHR | |
| SCHEMBL8132478 | 0.67 | SLC9A1 (0.62) | ALDH1A1MAPTLMNASMN1; SMN2SLC9A1 | |
| SCHEMBL868057 | 0.67 | CHRNB2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |