Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 7/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912940 | 0.83 | ACHE (0.53) | ALDH1A1SMN1; SMN2KMT2AACHERAB9A | |
| SCHEMBL7911358 | 0.80 | SLC9A1 (0.38) | SLC9A1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7911273 | 0.75 | ALDH1A1 (0.33) | SLC9A1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8132478 | 0.74 | SLC9A1 (0.62) | SLC9A1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7910295 | 0.73 | SLC9A1 (0.65) | SLC9A1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7916736 | 0.69 | ACHE (0.51) | ALDH1A1SMN1; SMN2KMT2AACHERAB9A | |
| SCHEMBL8136170 | 0.68 | SLC9A1 (0.39) | SLC9A1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL927447 | 0.66 | SLC9A1 (0.39) | SLC9A1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL70795 | 0.65 | SMN1; SMN2 (0.65) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL5556431 | 0.65 | SLC9A1 (0.40) | SLC9A1MAPTALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |