Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911273 | 0.84 | ALDH1A1 (0.33) | SLC9A1HPGDTSHRKDM4EALDH1A1 | |
| SCHEMBL928773 | 0.83 | SLC9A1 (0.35) | SLC9A1ACHE | |
| SCHEMBL928776 | 0.82 | SLC9A1 (0.34) | SLC9A1ACHE | |
| SCHEMBL927447 | 0.80 | SLC9A1 (0.39) | SLC9A1HPGDTSHRKDM4EALDH1A1 | |
| SCHEMBL7913223 | 0.80 | ACHE (0.44) | TSHRKDM4EALDH1A1HSD17B10ACHE | |
| SCHEMBL7911358 | 0.79 | SLC9A1 (0.38) | SLC9A1HPGDTSHRKDM4EALDH1A1 | |
| SCHEMBL7912931 | 0.73 | SLC9A1 (0.59) | SLC9A1KDM4EALDH1A1ACHE | |
| SCHEMBL7916794 | 0.72 | SLC9A1 (0.61) | SLC9A1KDM4EALDH1A1ACHE | |
| SCHEMBL927184 | 0.72 | SLC9A1 (0.61) | SLC9A1KDM4EALDH1A1ACHE | |
| SCHEMBL7916773 | 0.72 | SLC9A1 (0.37) | SLC9A1KDM4EALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |