SCHEMBL79116

SCHEMBL79116

C[Si](C)(C)C#Cc1cccc(O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 2/20 0.49
CA12 O43570 3/20 0.45
CA2 P00918 3/20 0.45
CA9 Q16790 3/20 0.45
CA1 P00915 2/20 0.45
ALDH1A1 P00352 3/20 0.42
CYP3A4 P08684 2/20 0.42
CA14 Q9ULX7 2/20 0.42
LMNA P02545 1/20 0.42
CA5A P35218 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
FFAR1 O14842 2/20 0.41
PGK1 P00558 1/20 0.40
ACHE P22303 2/20 0.40
HSD17B13 Q7Z5P4 2/20 0.39
PIK3CD O00329 1/20 0.37
ABL1 P00519 1/20 0.37
PIK3CA P42336 1/20 0.37
PIK3CB P42338 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3614755 0.85 GRM5 (0.39) GRM5ALDH1A1CYP3A4CYP2C9
SCHEMBL718295 0.80 CA12 (0.60) GRM5CA12CA2CA9CA1
SCHEMBL5537819 0.80 GRM5 (0.40) GRM5CA12CA2CA9CA1
SCHEMBL20102200 0.79 GRM5 (0.45) GRM5CA12CA2CA9CA1
SCHEMBL23867871 0.78 APP (0.50) GRM5CA12CA2CA9CA1
SCHEMBL31349195 0.78 GRM5 (0.56) GRM5CA12CA2CA9CA1
SCHEMBL3347354 0.78 GRM5 (0.56) GRM5CA12CA2CA9CA1
SCHEMBL8788358 0.77 GRM5 (0.33) GRM5
SCHEMBL2473384 0.77 CYP1A2 (0.42) CYP3A4HSD17B10ABL1TSHRHSD17B1
SCHEMBL2814308 0.77 CA12 (0.49) GRM5CA12CA2CA9CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552781-B2 Epoxy compound, composition prepared therefrom, semiconductor device prepared therefrom, electronic device prepared therefrom, article prepared therefrom, and method of preparing article SAMSUNG ELECTRONICS CO., LTD. (KR) 2026-02-17 US disclosed
US-20240059829-A1 EPOXY COMPOUND, COMPOSITION PREPARED THEREFROM, SEMICONDUCTOR DEVICE PREPARED THEREFROM, ELECTRONIC DEVICE PREPARED THEREFROM, ARTICLE PREPARED THEREFROM, AND METHOD OF PREPARING ARTICLE SAMSUNG ELECTRONICS CO LTD (KR) 2024-02-22 US disclosed
CN-115583902-B Preparation method of alkynyl thioether compound 江苏医药职业学院 2024-02-13 CN disclosed
US-11827742-B2 Epoxy compound, composition prepared therefrom, semiconductor device prepared therefrom, electronic device prepared therefrom, article prepared therefrom, and method of preparing article SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-11-28 US disclosed
US-20230303493-A1 ANTIBACTERIAL ADJUVANTS AND APPLICATIONS THEREOF SAN JOSE STATE UNIVERSITY RESEARCH FOUNDATION 2023-09-28 US disclosed
US-20230303493-A1 ANTIBACTERIAL ADJUVANTS AND APPLICATIONS THEREOF SAN JOSE STATE UNIVERSITY RESEARCH FOUNDATION 2023-09-28 US disclosed
CN-115583902-A Preparation method of alkynyl thioether compound 江苏医药职业学院 2023-01-10 CN disclosed
US-20220056197-A1 EPOXY COMPOUND, COMPOSITION PREPARED THEREFROM, SEMICONDUCTOR DEVICE PREPARED THEREFROM, ELECTRONIC DEVICE PREPARED THEREFROM, ARTICLE PREPARED THEREFROM, AND METHOD OF PREPARING ARTICLE SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-02-24 US disclosed
EP-3957635-A1 EPOXY COMPOUND, COMPOSITION PREPARED THEREFROM, SEMICONDUCTOR DEVICE PREPARED THEREFROM, ELECTRONIC DEVICE PREPARED THEREFROM, ARTICLE PREPARED THEREFROM, AND METHOD OF PREPARING ARTICLE Samsung Electronics Co., Ltd. (KR) 2022-02-23 EP disclosed
CN-114075183-A Epoxy compounds, compositions, semiconductor devices, electronic devices, and articles prepared therefrom, and methods of making articles 三星电子株式会社 2022-02-22 CN disclosed
US-7579479-B2 Substituted acid derivatives useful as antidiabetic and antiobesity agents and method BRISTOL-MYERS SQUIBB COMPANY (US) 2009-08-25 US disclosed
US-7579479-B2 Substituted acid derivatives useful as antidiabetic and antiobesity agents and method BRISTOL-MYERS SQUIBB COMPANY (US) 2009-08-25 US disclosed
WO-2009036235-A2 INSECTICIDAL CARBAMATES EXHIBITING SPECIES-SELECTIVE INHIBITION OF ACETYLCHOLINESTERASE (ACHE) VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2009-03-19 WO disclosed
US-20090068242-A1 INSECTICIDAL CARBAMATES EXHIBITING SPECIES-SELECTIVE INHIBITION OF ACETYLCHOLINESTERASE (AChE) VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY 2009-03-12 US disclosed
US-7291692-B2 Polyarylene oxide and method of producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-11-06 US disclosed
US-7241780-B2 Substituted acid derivatives useful as antidiabetic and antiobesity agents and method BRISTOLS-MYERS SQUIBB COMPANY (US) 2007-07-10 US disclosed
US-7241780-B2 Substituted acid derivatives useful as antidiabetic and antiobesity agents and method BRISTOLS-MYERS SQUIBB COMPANY (US) 2007-07-10 US disclosed
US-20070015797-A1 Substituted acid derivatives useful as antidiabetic and antiobesity agents and method CHENG PETER T 2007-01-18 US disclosed
US-20070015797-A1 Substituted acid derivatives useful as antidiabetic and antiobesity agents and method CHENG PETER T 2007-01-18 US disclosed
US-20050096452-A1 Polyarylene oxide and method of producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552781-B2 Epoxy compound, composition prepared therefrom, semiconductor device prepared therefrom, electronic device prepared therefrom, article prepared therefrom, and method of preparing article CHRM2, WEE2, CHRM1 GRM5 1319/4885CA12 3069/4885CA2 3910/4885
US-20230303493-A1 ANTIBACTERIAL ADJUVANTS AND APPLICATIONS THEREOF CAPG, SLC11A2, CAPRIN1 GRM5 3967/4885CA12 4192/4885CA2 3190/4885
US-20090068242-A1 INSECTICIDAL CARBAMATES EXHIBITING SPECIES-SELECTIVE INHIBITION OF ACETYLCHOLINESTERASE (AChE) ACHE, BCHE, CHAT GRM5 1033/4885CA12 1227/4885CA2 457/4885
US-20070015797-A1 Substituted acid derivatives useful as antidiabetic and antiobesity agents and method GPR119, LIPC, ACACA GRM5 2204/4885CA12 2497/4885CA2 1186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.