SCHEMBL2320565

SCHEMBL2320565

CC(=O)C1=CCc2ccccc2C1=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
CES1 P23141 2/20 0.44
MAOA P21397 1/20 0.44
BCHE P06276 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
S100A4 P26447 1/20 0.39
MAPT P10636 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HSP90AA1 P07900 1/20 0.38
HSP90AB1 P08238 1/20 0.38
MIF P14174 2/20 0.37
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
PKM P14618 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
KDM4E B2RXH2 1/20 0.37
STAT3 P40763 1/20 0.37
NOTUM Q6P988 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15573886 0.87 NOTUM (0.39) ALDH1A1CES1MAOACYP1A2S100A4
SCHEMBL30191469 0.87 NOTUM (0.39) ALDH1A1CES1MAOACYP1A2S100A4
SCHEMBL3039377 0.84 MAOA (0.45) ALDH1A1CES1MAOABCHECYP1A2
SCHEMBL9623401 0.81 ALDH1A1 (0.41) ALDH1A1CES1MAOABCHECYP1A2
SCHEMBL8003247 0.79 CES1 (0.41) ALDH1A1CES1MAOABCHECYP1A2
SCHEMBL10440547 0.79 ALDH1A1 (0.42) ALDH1A1CES1MAOABCHECYP1A2
SCHEMBL8154115 0.76 MAPT (0.43) ALDH1A1CES1MAOAMAPTSMN1; SMN2
SCHEMBL335207 0.75 SRD5A2 (0.43) ALDH1A1CES1MAOASMN1; SMN2KDM4E
SCHEMBL11813906 0.75 HTR6 (0.37) ALDH1A1CES1MAOABCHECYP1A2
SCHEMBL31147237 0.75 SRD5A2 (0.43) ALDH1A1CES1MAOASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240306688-A1 METHOD OF MITIGATING OFF-ODORS GIVAUDAN SA (CH) 2024-09-19 US claimed
EP-4391827-A1 METHOD OF MITIGATING OFF-ODORS Givaudan SA (CH) 2024-07-03 EP claimed
WO-2023025549-A1 METHOD OF MITIGATING OFF-ODORS GIVAUDAN SA (CH) 2023-03-02 WO claimed
US-20240306688-A1 METHOD OF MITIGATING OFF-ODORS GIVAUDAN SA (CH) 2024-09-19 US disclosed
EP-4391827-A1 METHOD OF MITIGATING OFF-ODORS Givaudan SA (CH) 2024-07-03 EP disclosed
WO-2023025549-A1 METHOD OF MITIGATING OFF-ODORS GIVAUDAN SA (CH) 2023-03-02 WO disclosed
US-10487189-B2 Method of making a foam SEALED AIR CORPORATION (US) (US) 2019-11-26 US disclosed
EP-2352785-B1 METHODS AND COMPOSITIONS FOR COATING PIPE UPONOR INNOVATION AB (SE) 2018-08-22 EP disclosed
US-9937527-B2 Methods for coating pipe UPONOR INNOVATION AB (FI) 2018-04-10 US disclosed
US-9656298-B2 Compositions for coating pipe UPONOR INNOVATION AB (SE) 2017-05-23 US disclosed
US-20160096942-A1 Method of Making a Foam SEALED AIR CORPORATION (US) (US) 2016-04-07 US disclosed
US-6583154-B1 Neuropeptide Y antagonist; pyrrolo-(3,2-b)pyridines and pyrrolo-(3,2-d)pyrimidines AMGEN INC. 2003-06-24 US disclosed
US-20020197482-A1 Multilayer polymeric article with intercrosslinked polymer layers and method of making same SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION 2002-12-26 US disclosed
EP-1114052-A1 4-AMINOPYRROLOPYRIMIDINES AS KINASE INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 2001-07-11 EP disclosed
US-6218581-B1 SOLVENT EXTRACTION OF WATER SOLUBLE PROTEIN FROM BEAN OR GRAIN; ISOLATION, PURIFICATION OF ACYLATED FORM; HYDROLYSIS SANYO SHOKUHIN CO., LTD. (JP) 2001-04-17 US disclosed
EP-1054887-A1 BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS Amgen Inc. (US) 2000-11-29 EP disclosed
WO-2000017202-A1 4-AMINOPYRROLOPYRIMIDINES AS KINASE INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 2000-03-30 WO disclosed
EP-0978567-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOLS SANYO SHOKUHIN CO., LTD. (JP) 2000-02-09 EP disclosed
WO-1999040091-A1 BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS AMGEN INC. (US) 1999-08-12 WO disclosed
US-4158094-A BLOWING AGENTS GENERAL ELECTRIC COMPANY (US) 1979-06-12 US disclosed