Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904610 | 0.90 | THRB (0.55) | THRBMAPTTP53KDRGAA | |
| SCHEMBL7913339 | 0.89 | THRB (0.62) | THRBMAPTTP53LMNAKDR | |
| SCHEMBL7912149 | 0.86 | THRB (0.50) | THRBMAPTTP53LMNAKDR | |
| SCHEMBL7918649 | 0.83 | MAPT (0.54) | MAPTTP53LMNAGAAALDH1A1 | |
| SCHEMBL7913404 | 0.83 | MAPT (0.50) | MAPTTP53LMNAGAAALDH1A1 | |
| SCHEMBL7914883 | 0.80 | MAPT (0.62) | THRBMAPTTP53LMNAKDR | |
| SCHEMBL7918641 | 0.79 | MAPT (0.45) | MAPTTP53LMNAGAACNR1 | |
| SCHEMBL7918619 | 0.78 | THRB (0.69) | THRBMAPTTP53KDRGAA | |
| SCHEMBL7904904 | 0.77 | CA1 (0.50) | MAPTTP53LMNAKDRALDH1A1 | |
| SCHEMBL7913378 | 0.77 | MAPT (0.55) | MAPTTP53LMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |