Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7919815 | 0.94 | NFKB1 (0.52) | LMNATSHRCYP1A2CYP2C19ADORA3 | |
| SCHEMBL7906162 | 0.86 | SMPD1 (0.51) | LMNAALDH1A1ADRB2ADRB3SMN1; SMN2 | |
| SCHEMBL11429666 | 0.80 | CA12 (0.46) | LMNATSHRCYP2C19ALDH1A1ADRB2 | |
| SCHEMBL6576604 | 0.78 | ADRA1A (0.77) | LMNATSHRCYP1A2CYP2C19ADORA3 | |
| SCHEMBL11818791 | 0.78 | KMT2A (0.52) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL29511863 | 0.77 | HIF1A (0.58) | LMNATSHRCYP1A2ADORA3ADRA1A | |
| SCHEMBL3652526 | 0.77 | HIF1A (0.58) | LMNATSHRCYP1A2ADORA3ADRA1A | |
| SCHEMBL11429840 | 0.77 | SLC22A3 (0.49) | LMNATSHRALDH1A1ADRB2CYP3A4 | |
| SCHEMBL11002220 | 0.77 | SMN1; SMN2 (0.62) | LMNAALDH1A1ACHESMN1; SMN2 | |
| SCHEMBL21709181 | 0.77 | LMNA (0.41) | LMNATSHRCYP1A2CYP2C19ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265402-B1 | ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-0924204-A1 | 2-PHENYLMORPHOLIN-5-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-06-23 | — | — | EP | disclosed |