Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | F7 | P08709 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913469 | 0.86 | LMNA (0.48) | BCHEALDH1A1ADRB3ADRB2SMN1; SMN2 | |
| SCHEMBL7919815 | 0.81 | NFKB1 (0.52) | ALDH1A1ADRB3ADRB2SMN1; SMN2LMNA | |
| SCHEMBL323396 | 0.80 | LTA4H (0.48) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL8843624 | 0.80 | SMPD1 (0.53) | SMPD1HDAC1HDAC8HDAC6F2 | |
| SCHEMBL30839672 | 0.79 | MTNR1A (0.53) | SMPD1HDAC1HDAC8HDAC6MTNR1A | |
| SCHEMBL7916416 | 0.78 | NFKB1 (0.57) | SMPD1HDAC1HDAC8HDAC6F2 | |
| SCHEMBL7823960 | 0.78 | SMPD1 (0.57) | SMPD1HDAC1HDAC8HDAC6F2 | |
| SCHEMBL30352666 | 0.78 | NFKB1 (0.57) | SMPD1HDAC1HDAC8HDAC6F2 | |
| SCHEMBL11811306 | 0.77 | ADRB2 (0.73) | MTNR1AMTNR1BBCHEALDH1A1ADRB3 | |
| SCHEMBL2060104 | 0.77 | SMPD1 (0.56) | SMPD1HDAC1HDAC8HDAC6F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265402-B1 | ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-0924204-A1 | 2-PHENYLMORPHOLIN-5-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-06-23 | — | — | EP | disclosed |