Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879464 | 0.83 | TSHR (0.49) | TSHRHSD17B10MEN1TP53CYP3A4 | |
| SCHEMBL10465908 | 0.81 | TYR (0.47) | TSHRHSD17B10MEN1TP53CYP3A4 | |
| SCHEMBL17672760 | 0.80 | TTR (0.36) | CA12CA2CA3CA6CA9 | |
| SCHEMBL17672994 | 0.80 | ALDH1A1 (0.34) | CA12CA2CA3CA6CA9 | |
| SCHEMBL6214320 | 0.78 | KLF10 (0.46) | KDM1AMAOACA12CA2CA3 | |
| SCHEMBL1400680 | 0.77 | ALOX5 (0.46) | CA12CA2CA3CA6CA9 | |
| SCHEMBL580272 | 0.77 | ALOX15 (0.50) | BCHEACHETSHRHSD17B10MEN1 | |
| SCHEMBL581502 | 0.77 | ALOX15 (0.50) | BCHEACHETSHRHSD17B10MEN1 | |
| SCHEMBL586745 | 0.77 | ALOX15 (0.50) | BCHEACHETSHRHSD17B10MEN1 | |
| SCHEMBL9453919 | 0.77 | ALOX15 (0.50) | BCHEACHETSHRHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6215001-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |