Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.43 |
| ▸ | ABAT | P80404 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220634 | 1.00 | ALDH1A1 (0.49) | ALDH1A1GPR35MAPK1SMN1; SMN2TP53 | |
| SCHEMBL31693329 | 1.00 | ALDH1A1 (0.49) | ALDH1A1GPR35MAPK1SMN1; SMN2TP53 | |
| SCHEMBL4594016 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MAPK1HTTRAB9AL3MBTL1 | |
| SCHEMBL488895 | 0.83 | GPR35 (0.47) | ALDH1A1GPR35MAPK1SMN1; SMN2TP53 | |
| SCHEMBL8568179 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAPK1TSHRHTTRAB9A | |
| SCHEMBL28763126 | 0.77 | ALDH1A1 (0.48) | ALDH1A1GPR35SMN1; SMN2HPGDHTT | |
| Ethylene SCHEMBL27749127 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MAPK1TSHRHTTRAB9A | |
| SCHEMBL5921938 | 0.76 | CTSB (0.61) | ALDH1A1SMN1; SMN2TP53HPGDTSHR | |
| SCHEMBL56332 | 0.75 | ALDH1A1 (0.49) | ALDH1A1MAPK1TSHRHTTRAB9A | |
| SCHEMBL227454 | 0.75 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HTTRAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101570508-A | Separation and purification of 4-hydroxy-3-nitropyridine by sublimation method | UNIV JIANGSU POLYTECHNIC (CN) | 2009-11-04 | — | — | CN | claimed |
| EP-0932405-A4 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BECKMAN CORP (US) | 2001-10-17 | — | — | EP | disclosed |
| EP-0932405-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-04 | — | — | EP | disclosed |
| WO-1997049400-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-31 | — | — | WO | disclosed |