SCHEMBL7915469

SCHEMBL7915469

O=c1c(-c2ccccc2)ccc(Br)cc1-c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.53
S100A4 P26447 1/20 0.50
PTGDR2 Q9Y5Y4 1/20 0.47
MAPK1 P28482 3/20 0.44
ALDH1A1 P00352 2/20 0.44
AKR1C3 P42330 1/20 0.44
AKR1C2 P52895 1/20 0.44
AKR1C1 Q04828 1/20 0.44
BCL2 P10415 1/20 0.42
MCL1 Q07820 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA4 P22748 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
ALOX5 P09917 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CYP1A2 P05177 1/20 0.42
BIRC5 O15392 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL364027 0.82 MAPK1 (0.52) PTPRCS100A4PTGDR2MAPK1ALDH1A1
SCHEMBL19190198 0.82 PTPRC (0.56) PTPRCS100A4PTGDR2MAPK1ALDH1A1
SCHEMBL30006434 0.82 MAPK1 (0.52) PTPRCS100A4PTGDR2MAPK1ALDH1A1
SCHEMBL2200354 0.78 MAPK1 (0.61) PTPRCS100A4PTGDR2MAPK1ALDH1A1
SCHEMBL2171715 0.78 MAPK1 (0.61) PTPRCS100A4PTGDR2MAPK1ALDH1A1
SCHEMBL7914987 0.77 LMNA (0.55) PTPRCS100A4MAPK1ALDH1A1TDP1
SCHEMBL4174406 0.76 ALDH1A1 (0.58) PTPRCS100A4PTGDR2MAPK1ALDH1A1
SCHEMBL29635316 0.76 ALDH1A1 (0.58) PTPRCS100A4PTGDR2MAPK1ALDH1A1
SCHEMBL3007914 0.76 MAPK1 (0.58) PTPRCS100A4PTGDR2MAPK1ALDH1A1
SCHEMBL2200357 0.75 NPC1 (0.47) PTPRCS100A4PTGDR2MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed