Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7923508 | 0.95 | MEN1 (0.44) | HTR1ACA12CA9MAPTALDH1A1 | |
| SCHEMBL7915534 | 0.92 | MAPT (0.44) | CA12CA9MAPTALDH1A1HTT | |
| SCHEMBL7923972 | 0.88 | LMNA (0.44) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL7921447 | 0.88 | CA12 (0.47) | HTR1ACA12CA9MAPTALDH1A1 | |
| SCHEMBL7927355 | 0.87 | DRD2 (0.46) | CA12CA9MAPTALDH1A1HTT | |
| SCHEMBL7921529 | 0.87 | LMNA (0.55) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7923530 | 0.86 | CA12 (0.48) | HTR1ACA12CA9MAPTALDH1A1 | |
| SCHEMBL7921790 | 0.83 | DRD2 (0.46) | CA12CA9MAPTALDH1A1HTT | |
| SCHEMBL7915494 | 0.83 | LMNA (0.45) | MAPTALDH1A1HTTLMNATSHR | |
| SCHEMBL7915565 | 0.82 | LMNA (0.56) | HTR1AMAPTALDH1A1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |