Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 9/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NFKBIA | P25963 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 6/20 | 0.37 |
| ▸ | CA1 | P00915 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915976 | 0.74 | MEN1 (0.39) | SLC40A1KDM4ENFKBIALMNAKMT2A | |
| SCHEMBL812924 | 0.72 | CA12 (0.47) | KDM4ELMNAKMT2AMAPTNPSR1 | |
| SCHEMBL30442903 | 0.72 | CA12 (0.47) | KDM4ELMNAKMT2AMAPTNPSR1 | |
| SCHEMBL30443299 | 0.71 | CA12 (0.46) | KDM4ELMNAKMT2AMAPTNPSR1 | |
| SCHEMBL6618561 | 0.69 | SLC40A1 (0.35) | SLC40A1KDM4ENFKBIALMNAKMT2A | |
| SCHEMBL3187233 | 0.69 | KDM4E (0.44) | SLC40A1KDM4ELMNAKMT2AMAPT | |
| SCHEMBL22097608 | 0.69 | ALDH1A1 (0.39) | KDM4ELMNAKMT2AMAPTHSD17B10 | |
| SCHEMBL7700407 | 0.68 | CA12 (0.63) | KDM4ELMNAKMT2AALDH1A1HTT | |
| SCHEMBL6617936 | 0.68 | SLC40A1 (0.34) | SLC40A1KDM4ENFKBIALMNAKMT2A | |
| SCHEMBL7786854 | 0.66 | SLC40A1 (0.35) | SLC40A1KDM4ENFKBIALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221889-B1 | INTERLEUKIN ANTAGONIST; SKIN DISORDERS, RESPIRATORY SYSTEM DISORDERS, RHEUMATIC DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2001-04-24 | — | — | US | disclosed |