Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916009 | 0.74 | SLC40A1 (0.39) | MEN1MAPTKMT2AKDM4ETDP1 | |
| SCHEMBL4612017 | 0.68 | PARP1 (0.53) | MEN1MAPTKMT2AKDM4ETDP1 | |
| SCHEMBL812924 | 0.68 | CA12 (0.47) | MEN1MAPTKMT2AKDM4ETDP1 | |
| SCHEMBL30442903 | 0.68 | CA12 (0.47) | MEN1MAPTKMT2AKDM4ETDP1 | |
| Pyrene SCHEMBL27684019 | 0.67 | ALDH1A1 (0.63) | MEN1MAPTKMT2AKDM4ETDP1 | |
| SCHEMBL30834919 | 0.67 | RET (0.56) | MEN1MAPTKMT2AKDM4ETDP1 | |
| SCHEMBL4945188 | 0.67 | RET (0.56) | MEN1MAPTKMT2AKDM4ETDP1 | |
| SCHEMBL187697 | 0.66 | ALDH1A1 (0.61) | MEN1MAPTKMT2AKDM4ETDP1 | |
| SCHEMBL29626558 | 0.66 | ALDH1A1 (0.61) | MEN1MAPTKMT2AKDM4ETDP1 | |
| 1-Nitropyrene SCHEMBL339725 | 0.66 | ALDH1A1 (0.57) | MEN1MAPTKMT2AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221889-B1 | INTERLEUKIN ANTAGONIST; SKIN DISORDERS, RESPIRATORY SYSTEM DISORDERS, RHEUMATIC DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2001-04-24 | — | — | US | disclosed |