Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 8/20 | 0.47 |
| ▸ | CA1 | P00915 | 8/20 | 0.47 |
| ▸ | CA2 | P00918 | 8/20 | 0.47 |
| ▸ | CA4 | P22748 | 8/20 | 0.47 |
| ▸ | CA7 | P43166 | 8/20 | 0.47 |
| ▸ | CA9 | Q16790 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | GRK5 | P34947 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30442903 | 1.00 | CA12 (0.47) | CA12CA1CA2CA4CA7 | |
| SCHEMBL30443299 | 0.98 | CA12 (0.46) | CA12CA1CA2CA4CA7 | |
| SCHEMBL9635462 | 0.81 | CA12 (0.38) | CA12CA1CA2CA4CA7 | |
| SCHEMBL8336188 | 0.77 | CA12 (0.64) | CA12CA1CA2CA4CA7 | |
| SCHEMBL22097608 | 0.76 | ALDH1A1 (0.39) | CA12CA1CA2CA4CA7 | |
| SCHEMBL7700407 | 0.75 | CA12 (0.63) | CA12CA1CA2CA4CA7 | |
| SCHEMBL6997307 | 0.72 | CYP4F2 (0.33) | CA12CA1CA2CA4CA7 | |
| SCHEMBL7916009 | 0.72 | SLC40A1 (0.39) | CA12CA1CA2CA4CA7 | |
| SCHEMBL13483763 | 0.72 | CA12 (0.39) | CA12CA1CA2CA4CA7 | |
| SCHEMBL6616713 | 0.72 | CA12 (0.42) | CA12CA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4838934-B2 | — | — | 2011-12-14 | — | — | JP | claimed |
| EP-1042291-B1 | ARYL-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | KLINGE CO CHEM PHARM FAB (DE) | 2005-07-13 | — | — | EP | claimed |
| EP-0937052-B1 | PROCESS FOR THE PREPARATION OF 1,8-NAPHTHOSULTAM | CIBA SC HOLDING AG (CH) | 2001-06-20 | — | — | EP | claimed |
| EP-1042291-A1 | ARYL-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | Klinge Pharma GmbH (DE) | 2000-10-11 | — | — | EP | claimed |
| US-6046339-A | Process for the preparation of 1, 8-naphthosultam | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-04-04 | — | — | US | claimed |
| WO-1999031064-A1 | ARYL-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | KLINGE PHARMA GMBH (DE) | 1999-06-24 | — | — | WO | claimed |
| EP-0192492-B1 | PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1992-01-02 | — | — | EP | claimed |
| JP-3152142-A | — | — | None | — | — | JP | disclosed |
| EP-3402777-B1 | OXAZOLIDINONES AS TARO INHIBITORS | MERCK SHARP & DOHME (US) | 2023-12-13 | — | — | EP | disclosed |
| US-20230288610-A1 | WAVELENGTH SELECTIVE ABSORPTION FILTER AND DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2023-09-14 | — | — | US | disclosed |
| US-20230288610-A1 | WAVELENGTH SELECTIVE ABSORPTION FILTER AND DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2023-09-14 | — | — | US | disclosed |
| US-11752128-B2 | Benzimidazoles and indoles as taro inhibitors | MERCK SHARP & DOHME CORPORATION (US) | 2023-09-12 | — | — | US | disclosed |
| US-11738010-B2 | Oxazolidinones as TarO inhibitors | MERCK SHARP & DOHME CORP. (US) | 2023-08-29 | — | — | US | disclosed |
| US-5036075-A | Serotonin antagonists | RHONE-POULENC SANTE (FR) | 1991-07-30 | — | — | US | disclosed |
| JP-H03152142-A | CRYSTALLINE PROPYLENE POLYMER COMPOSITION | MITSUBISHI PETROCHEM CO LTD | 1991-06-28 | — | — | JP | disclosed |
| US-5021420-A | Antiserotonine agents; central nervous system, gastroin-testinal and cardiovascular disorders | RHONE-POULENC SANTE (FR) | 1991-06-04 | — | — | US | disclosed |
| EP-0239050-A1 | 2,3-Dihydro-2-phenyl-5-aminoalkyl-naphto ¬1,8-bc -1,5-thiazocin-4 (5H)-one derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1987-09-30 | — | — | EP | disclosed |
| US-4677193-A | GONADOTROPIN-RELEASING FACTOR ANALOGS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1987-06-30 | — | — | US | disclosed |
| US-4640930-A | CALCIUM CHANNEL BLOCKERS | HOFFMANN-LA ROCHE INC. (US) | 1987-02-03 | — | — | US | disclosed |
| EP-0192492-A2 | Peptides containing an aliphatic-aromatic ketone side chain | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1986-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11752128-B2 | Benzimidazoles and indoles as taro inhibitors | CSDE1, IDO1, TMBIM6 | CA12 4765/4885CA1 4732/4885CA2 3819/4885 |
| US-11738010-B2 | Oxazolidinones as TarO inhibitors | OXA1L, DDO, ALPI | CA12 4692/4885CA1 4655/4885CA2 4210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.