Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7488455 | 0.83 | ATAD2 (0.40) | P2RY2KDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL7503021 | 0.81 | P2RY2 (0.42) | P2RY2KDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL7503494 | 0.78 | LMNA (0.33) | P2RY2KDM4EALDH1A1POLBLMNA | |
| SCHEMBL7840803 | 0.78 | ATAD2 (0.38) | P2RY2KDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL7486706 | 0.77 | P2RY2 (0.37) | P2RY2KDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL7505786 | 0.76 | GRM7 (0.35) | P2RY2KDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL7491592 | 0.76 | ALDH1A1 (0.45) | P2RY2KDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL7840949 | 0.76 | P2RY2 (0.39) | P2RY2KDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL7491074 | 0.75 | P2RY2 (0.34) | P2RY2KDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL7490690 | 0.75 | P2RY2 (0.40) | P2RY2KDM4EALDH1A1HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218376-B1 | FOR TREATING INFLAMMATORY DISEASES | ASTRAZENECA UK LIMITED (GB) | 2001-04-17 | — | — | US | disclosed |