Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 5/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.53 |
| ▸ | PDE4A | P27815 | 5/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906256 | 0.87 | PDE4B (0.53) | PDE4BPDE4DPDE4APDE4CLMNA | |
| SCHEMBL7916424 | 0.84 | PDE4B (0.49) | PDE4BPDE4DPDE4APDE4CLMNA | |
| SCHEMBL7906155 | 0.82 | PDE4D (0.53) | PDE4BPDE4DPDE4APDE4CMAOA | |
| SCHEMBL8312871 | 0.81 | PDE4B (0.52) | PDE4BPDE4DPDE4APDE4CKMT2A | |
| SCHEMBL11435807 | 0.80 | PDE4B (0.77) | PDE4BPDE4DPDE4APDE4CMAOA | |
| SCHEMBL6584071 | 0.72 | PDE4B (0.59) | PDE4BPDE4DPDE4APDE4CMAOA | |
| SCHEMBL7763939 | 0.71 | PDE4B (0.64) | PDE4BPDE4DPDE4APDE4CLMNA | |
| SCHEMBL7764115 | 0.71 | PDE4B (0.82) | PDE4BPDE4DPDE4APDE4CLMNA | |
| SCHEMBL7760278 | 0.71 | PDE4B (0.82) | PDE4BPDE4DPDE4APDE4CLMNA | |
| SCHEMBL8486179 | 0.71 | PDE4B (0.67) | PDE4BPDE4DPDE4APDE4CMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265402-B1 | ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-0924204-A1 | 2-PHENYLMORPHOLIN-5-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-06-23 | — | — | EP | disclosed |