Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913827 | 0.85 | ALOX15 (0.36) | DHODHALOX15HTTF2PLG | |
| SCHEMBL16502454 | 0.85 | HTT (0.54) | HDAC6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7916646 | 0.84 | DHODH (0.48) | HDAC6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7916811 | 0.83 | CCNT1 (0.40) | HDAC8PDE10AALOX15HTTRAB9A | |
| SCHEMBL7921982 | 0.78 | HTR5A (0.45) | HDAC6DHODHPDE10A | |
| SCHEMBL7917796 | 0.75 | PLAU (0.35) | F2PLGPLAUPLATKLK1 | |
| SCHEMBL7919038 | 0.74 | PLAU (0.36) | F2PLGPLAUPLATKLK1 | |
| SCHEMBL7915719 | 0.74 | RAB9A (0.40) | NPC1RAB9ALMNAMAPT | |
| SCHEMBL7911006 | 0.74 | HDAC8 (0.40) | HDAC6HDAC8PLAUNPC1RAB9A | |
| SCHEMBL7916552 | 0.73 | PLAU (0.34) | JAK3F2PLGPLAUPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090304-A1 | ACYLGUANIDINE DERIVATIVE | アステラス製薬株式会社 (JP) | 2010-08-12 | — | — | WO | disclosed |