Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7593525 | 0.89 | TAS2R14 (0.41) | TAS2R14NPC1RAB9ANR4A2ALDH1A1 | |
| SCHEMBL7590097 | 0.81 | TAS2R14 (0.41) | TAS2R14NPC1RAB9ANR4A2ALDH1A1 | |
| SCHEMBL7596743 | 0.79 | NR4A2 (0.40) | NR4A2SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL7594873 | 0.79 | HCAR3 (0.36) | NPC1RAB9ANR4A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7593036 | 0.77 | TAS2R14 (0.42) | TAS2R14ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7594765 | 0.76 | ALDH1A1 (0.38) | ALDH1A1CYP1A2CYP3A4CYP2C19LMNA | |
| SCHEMBL7598805 | 0.76 | TSPO (0.43) | TAS2R14ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7596127 | 0.75 | TSPO (0.48) | TAS2R14ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL27634015 | 0.75 | TSHR (0.49) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7593565 | 0.74 | LTB4R2 (0.43) | TAS2R14ALDH1A1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211177-B1 | SIDE EFFECT REDUCTION | CELL PATHWAYS, INC. | 2001-04-03 | — | — | US | disclosed |