Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7593525 | 0.88 | TAS2R14 (0.41) | TAS2R14ALDH1A1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL7598805 | 0.88 | TSPO (0.43) | TAS2R14ALDH1A1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL7594765 | 0.87 | ALDH1A1 (0.38) | ALDH1A1CYP3A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL7596127 | 0.86 | TSPO (0.48) | TAS2R14ALDH1A1LMNA | |
| SCHEMBL7594893 | 0.84 | LTB4R2 (0.42) | ALDH1A1 | |
| SCHEMBL7595160 | 0.84 | POLB (0.42) | TAS2R14ALDH1A1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL7596184 | 0.83 | LTB4R2 (0.39) | ALDH1A1CYP3A4LMNA | |
| SCHEMBL7595241 | 0.82 | PTGES (0.46) | ALDH1A1KMT2ACYP1A2MEN1 | |
| SCHEMBL7596743 | 0.82 | NR4A2 (0.40) | KMT2APOLBHCAR3MEN1 | |
| SCHEMBL7594873 | 0.82 | HCAR3 (0.36) | ALDH1A1KMT2ACYP3A4CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020082280-A1 | Method of inhibiting neoplastic cells with benzimidazole derivatives | OSI PHARMACEUTICALS, INC. | 2002-06-27 | — | — | US | disclosed |
| US-6348032-B1 | POTENT COMPOUNDS THAT INDUCE APOPTOSIS IN NEOPLASTIC CELLS (BUT NOT SUBSTANTIALLY IN NORMAL CELLS), WITHOUT SUBSTANTIALLY INHIBITING PGE-2. | CELL PATHWAYS, INC. | 2002-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020082280-A1 | Method of inhibiting neoplastic cells with benzimidazole derivatives | MKI67, CCNI, TMBIM6 | TAS2R14 3615/4885ALDH1A1 487/4885KMT2A 1590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.