Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 2/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917010 | 0.83 | MAOB (0.33) | ALDH1A1MAPTALOX12CXCR2LMNA | |
| SCHEMBL7914051 | 0.82 | SLC6A3 (0.35) | ALDH1A1MEN1KMT2AMAPTALOX12 | |
| SCHEMBL7902850 | 0.81 | PGR (0.33) | ESR2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7907060 | 0.78 | ALOX5 (0.42) | ALDH1A1MAPTHPGDCYP1A2CYP2C19 | |
| SCHEMBL7916991 | 0.78 | SLC6A3 (0.42) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL7911686 | 0.78 | PGR (0.34) | ESR2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7930844 | 0.70 | PGR (0.33) | ESR2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7910125 | 0.66 | PGR (0.34) | ESR2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7911681 | 0.66 | MAPT (0.36) | ALDH1A1MEN1KMT2AMAPTALOX12 | |
| SCHEMBL7913175 | 0.65 | MAOB (0.33) | ALDH1A1MAPTALOX12PGRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059838-A2 | PDE4 INHIBITORS SELECTIVE FOR THE LONG FORM OF PDE4 FOR TREATING INFLAMMATION AND AVOIDING SIDE EFFECTS | DECODE GENETICS EHF (IS) | 2010-05-27 | — | — | WO | disclosed |
| WO-2010059836-A1 | SUBSTITUTED AZA-BRIDGED BICYCLICS FOR CARDIOVASCULAR AND CNS DISEASE | DECODE GENETICS EHF (IS) | 2010-05-27 | — | — | WO | disclosed |