Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SREBF2 | Q12772 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12070947 | 0.91 | KDM4E (0.41) | ALDH1A1KDM4ETDP1MAPTLMNA | |
| SCHEMBL3625504 | 0.84 | MAPT (0.40) | ALDH1A1KDM4EMAPTLMNAHPGD | |
| SCHEMBL3671740 | 0.81 | FPR2 (0.37) | ALDH1A1KDM4ETDP1MAPTLMNA | |
| SCHEMBL313693 | 0.80 | CTSS (0.38) | ALDH1A1KDM4ETDP1MAPTLMNA | |
| SCHEMBL1232405 | 0.79 | ALDH1A1 (0.35) | ALDH1A1KDM4ETDP1MAPTLMNA | |
| SCHEMBL312942 | 0.79 | ALDH1A1 (0.35) | ALDH1A1KDM4EMAPTLMNAHPGD | |
| SCHEMBL996348 | 0.77 | SMPD3 (0.47) | KDM4EMAPTLMNAGAAGFER | |
| SCHEMBL15216080 | 0.75 | ALDH1A1 (0.40) | ALDH1A1KDM4ETDP1MAPTLMNA | |
| SCHEMBL4178311 | 0.74 | PDE10A (0.35) | ALDH1A1KDM4EMAPTHPGDGAA | |
| SCHEMBL313767 | 0.73 | MAPT (0.39) | ALDH1A1KDM4EMAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010088394-A1 | COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-08-05 | — | — | WO | disclosed |