Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822529 | 0.91 | ALDH1A1 (0.60) | ALDH1A1HSD17B10TDP1CA12CA1 | |
| SCHEMBL35155 | 0.83 | ALDH1A1 (0.48) | ALDH1A1HSD17B10TDP1CA12CA1 | |
| SCHEMBL40244 | 0.83 | CA2 (0.61) | ALDH1A1HSD17B10TDP1CA12CA1 | |
| SCHEMBL28554454 | 0.83 | ALDH1A1 (0.48) | ALDH1A1HSD17B10TDP1CA12CA1 | |
| SCHEMBL4654362 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TDP1CA12CA1 | |
| SCHEMBL9537305 | 0.82 | SRD5A2 (0.64) | ALDH1A1HSD17B10TDP1CA12CA1 | |
| Hydrochloric Acid SCHEMBL35156 | 0.81 | CA2 (0.59) | ALDH1A1HSD17B10TDP1CA12CA1 | |
| SCHEMBL7347493 | 0.81 | CA2 (0.65) | ALDH1A1HSD17B10TDP1CA12CA1 | |
| Hydrochloric Acid SCHEMBL7053219 | 0.81 | CA2 (0.59) | ALDH1A1HSD17B10TDP1CA12CA1 | |
| SCHEMBL7347488 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HSD17B10TDP1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214882-B1 | Benzenesulphonamide derivatives, preparation thereof and therapeutical uses thereof | SYNTHELABO (FR) | 2001-04-10 | — | — | US | disclosed |
| CN-1198735-A | Benzenesulfonamide derivatives, their preparation and their use in medicine | SYNTHELABO (FR) | 1998-11-11 | — | — | CN | disclosed |
| EP-0178183-B1 | PREPARATION OF AROMATIC KETONE-SULFONE COPOLYMERS | RAYCHEM CORPORATION (a Delaware corporation) (US) | 1993-01-20 | — | — | EP | disclosed |
| US-4593086-A | From carboxylic acid halide and aromatic dicarboxylic acid dihalide | RAYCHEM CORPORATION (US) | 1986-06-03 | — | — | US | disclosed |
| EP-0178183-A2 | Preparation of aromatic ketone-sulfone copolymers | RAYCHEM CORPORATION (a Delaware corporation) (US) | 1986-04-16 | — | — | EP | disclosed |
| US-4150051-A | N-Cyanosulfonamide compounds | CIBA-GEIGY CORPORATION (US) | 1979-04-17 | — | — | US | disclosed |
| US-4080483-A | COATINGS, MOLDING MATERIALS, LAMINATION | CIBA-GEIGY CORPORATION (US) | 1978-03-21 | — | — | US | disclosed |
| US-4075185-A | ADDITION POLYMERIZATION | CIBA-GEIGY CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |
| US-4049711-A | POLYSULFONAMIDE MONOMERS | CIBA-GEIGY CORPORATION (US) | 1977-09-20 | — | — | US | disclosed |
| US-3944526-A | N-cyanosulfonamide resins and intermediates therefor and products thereof | CIBA-GEIGY CORPORATION (US) | 1976-03-16 | — | — | US | disclosed |