SCHEMBL40244

SCHEMBL40244

O=C(O)c1ccc(S(=O)(=O)Cl)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.61
CA1 P00915 5/20 0.61
CA12 O43570 5/20 0.61
CA9 Q16790 5/20 0.61
CA14 Q9ULX7 4/20 0.61
CA3 P07451 2/20 0.61
CA6 P23280 2/20 0.61
CA5A P35218 2/20 0.61
CA7 P43166 2/20 0.61
CA5B Q9Y2D0 2/20 0.61
CYP2C19 P33261 1/20 0.61
ALDH1A1 P00352 2/20 0.61
KMT2A Q03164 1/20 0.61
TSHR P16473 3/20 0.57
TP53 P04637 1/20 0.57
HSD17B10 Q99714 2/20 0.54
TDP1 Q9NUW8 1/20 0.54
ALOX15 P16050 1/20 0.52
F2 P00734 2/20 0.52
PRSS1 P07477 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7053219 0.98 CA2 (0.59) CA2CA1CA12CA9CA14
Hydrochloric Acid SCHEMBL35156 0.98 CA2 (0.59) CA2CA1CA12CA9CA14
SCHEMBL1729812 0.85 CA1 (0.51) CA2CA1CA12CA9CA14
SCHEMBL18547450 0.85 SRD5A2 (0.62) CA2CA1CA12CA9CA14
SCHEMBL7917653 0.83 ALDH1A1 (0.50) CA2CA1CA12CA9CA14
SCHEMBL35155 0.81 ALDH1A1 (0.48) CA2CA1CA12CA9CA14
SCHEMBL28554454 0.81 ALDH1A1 (0.48) CA2CA1CA12CA9CA14
SCHEMBL9822529 0.80 ALDH1A1 (0.60) CA2CA1CA12CA9CA14
SCHEMBL2917437 0.80 CA1 (0.67) CA2CA1CA12CA9CA14
SCHEMBL22349 0.80 CA1 (0.67) CA2CA1CA12CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118772112-B PROTAC medicine molecule targeting Fam20C as well as preparation method and application thereof 西南交通大学 2025-04-01 CN claimed
CN-118772112-A PROTAC medicine molecule targeting Fam20C as well as preparation method and application thereof 西南交通大学 2024-10-15 CN claimed
CN-117298108-A Androgen receptor and glucocorticoid receptor dual-target inhibitor and application thereof 浙江师范大学 2023-12-29 CN claimed
CN-117285922-A Integrated variable-viscosity fracturing fluid and preparation method thereof 山东普瑞思德石油技术有限公司 2023-12-26 CN claimed
CN-115109011-B Benzothiazole compound, preparation method and application 河北师范大学 2023-12-15 CN claimed
CN-115109011-A Benzothiazole compound, preparation method and application 河北师范大学 2022-09-27 CN claimed
CN-113908589-B Hydrophobic charge induction mode membrane chromatography medium of surface imprinted antibody and preparation method thereof 天津工业大学 2022-09-27 CN claimed
CN-113908589-A Hydrophobic charge induction mode membrane chromatography medium for surface imprinted antibody and preparation method thereof 天津工业大学 2022-01-11 CN claimed
CN-106832783-B Toughening modification method of epoxy resin 中冶建筑研究总院有限公司 2020-01-07 CN claimed
CN-107056768-A A kind of reversible proton pump inhibitor, preparation method and applications 三峡大学 2017-08-18 CN claimed
CN-101801949-A Sulfonamides as TRPM8 modulators JANSSEN PHARMACEUTICA NV 2010-08-11 CN claimed
EP-2183239-A1 SULFONAMIDES AS TRPM8 MODULATORS Janssen Pharmaceutica, N.V. (BE) 2010-05-12 EP claimed
EP-1308540-B1 Plating bath and method for depositing a metal layer on a substrate SHIPLEY CO LLC (US) 2010-01-20 EP claimed
US-20090264474-A1 SULFONAMIDES AS TRPM8 MODULATORS JANSSEN PHARMACEUTICA, N.V. (BE) 2009-10-22 US claimed
WO-2009012430-A1 SULFONAMIDES AS TRPM8 MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2009-01-22 WO claimed
WO-2006011719-A1 N-SUBSTITUTED-SULFAMOYLBENZOIC ACID DERIVATIVES, METHOD FOR PREPARING THEREOF AND ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING THE SAME B & C BIOPHARM CO., LTD. (KR) 2006-02-02 WO claimed
US-20040104124-A1 Plating bath and method for depositing a metal layer on a substrate SHIPLEY COMPANY, L.L.C. 2004-06-03 US claimed
US-6736954-B2 A METAL PLATING BATH COMPRISING METAL SALTS AND AN ADDITIVE CONSUMPTION INHIBITOR(A HETEROATOM ORGANIC COMPOUNDS WHICH MAY CONTAIN SULFUR, OXYGEN OR NITROGEN HETEROATOMS) IMPROVE THE BRIGHTNESS OF PLATED METAL AS WELL AS THE DUCTILITY SHIPLEY COMPANY, L.L.C. 2004-05-18 US claimed
EP-1308540-A1 Plating bath and method for depositing a metal layer on a substrate Shipley Co. L.L.C. (US) 2003-05-07 EP claimed
US-20030070934-A1 Plating bath and method for depositing a metal layer on a substrate SHIPLEY COMPANY, L.L.C. 2003-04-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090264474-A1 SULFONAMIDES AS TRPM8 MODULATORS TRPM8, TRPM5, TRPM2 CA2 264/4885CA1 1538/4885CA12 2056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.