SCHEMBL35155

SCHEMBL35155

O=C(Cl)c1ccc(S(=O)(=O)Cl)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
KMT2A Q03164 1/20 0.41
CA2 P00918 6/20 0.40
CA1 P00915 5/20 0.40
CA9 Q16790 4/20 0.40
CA12 O43570 3/20 0.40
CA14 Q9ULX7 3/20 0.40
CA3 P07451 1/20 0.40
CA6 P23280 1/20 0.40
CYP2C19 P33261 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
PHGDH O43175 1/20 0.39
FLT1 P17948 1/20 0.38
FLT4 P35916 1/20 0.38
KDR P35968 1/20 0.38
EGFR P00533 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11408710 0.94 CA12 (0.46) ALDH1A1HSD17B10TDP1KMT2ACA2
SCHEMBL9242846 0.88 ALDH1A1 (0.44) ALDH1A1HSD17B10KMT2ALMNAPOLB
SCHEMBL7994787 0.88 ALDH1A1 (0.44) ALDH1A1HSD17B10KMT2ALMNAPOLB
SCHEMBL724893 0.83 ALDH1A1 (0.50) ALDH1A1KMT2ALMNAPOLB
SCHEMBL7917653 0.83 ALDH1A1 (0.50) ALDH1A1HSD17B10TDP1KMT2ACA2
SCHEMBL40244 0.81 CA2 (0.61) ALDH1A1HSD17B10TDP1KMT2ACA2
SCHEMBL28554454 0.81 ALDH1A1 (0.48) ALDH1A1HSD17B10TDP1KMT2ACA2
SCHEMBL8747696 0.81 LMNA (0.52) ALDH1A1TDP1KMT2ACA2CA1
SCHEMBL4654362 0.80 ALDH1A1 (0.52) ALDH1A1HSD17B10TDP1KMT2ACA2
SCHEMBL599583 0.79 ENPP2 (0.54) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119977093-A Salt lake brine gradient lithium extraction method based on in-situ electrolysis driving 赣南科技学院 2025-05-13 CN claimed
EP-0154811-A2 Coupling agents between mineral fillers and polymers Plüss-Staufer AG (CH) 1985-09-18 EP claimed
WO-1985003505-A2 COUPLING AGENT BETWEEN MINERAL FILLERS AND POLYMERS PLÜSS-STAUFER AG (CH) 1985-08-15 WO claimed
US-20260042806-A1 NOVEL PORE MONOMERS AND PORES OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-02-12 US disclosed
US-20250325711-A1 COVALENT FLUORESCENT PROBES FOR CANNABINOID RECEPTOR 2 HOFFMANN-LA ROCHE INC. (US) 2025-10-23 US disclosed
US-12366579-B2 Sulfur-heterocycle exchange chemistry and uses thereof UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2025-07-22 US disclosed
EP-4577529-A2 COVALENT FLUORESCENT PROBES FOR CANNABINOID RECEPTOR 2 F. Hoffmann-La Roche AG (CH) 2025-07-02 EP disclosed
EP-4569330-A1 NOVEL PORE MONOMERS AND PORES Oxford Nanopore Technologies PLC (GB) 2025-06-18 EP disclosed
CN-119977093-A Salt lake brine gradient lithium extraction method based on in-situ electrolysis driving 赣南科技学院 2025-05-13 CN disclosed
CN-119630970-A Novel Kong Shanti and holes 牛津纳米孔科技公开有限公司 2025-03-14 CN disclosed
CN-119604489-A Covalent fluorescent probes for cannabinoid receptor 2 豪夫迈·罗氏有限公司 2025-03-11 CN disclosed
US-4086209-A Novel nitrogen-containing aromatic polymers and process for their preparation TEIJIN LIMITED (JA) 1978-04-25 US disclosed
US-4051107-A Microstructured high molecular weight-low viscosity polyester polymers HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-09-27 US disclosed
US-4051123-A Sulfonic-acid-group containing disazo dyestuffs CIBA-GEIGY AG (CH) 1977-09-27 US disclosed
US-4051106-A High molecular weight copolyester resins having a high degree of alternating structure HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-09-27 US disclosed
US-4049629-A PREPARING POLYESTERS BY REACTING A DIACID HALIDE AND A SUBSTITUTED BISPHENOL AND A GLYCOL HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-09-20 US disclosed
US-4031068-A Non-migratory sulfonyl azide antioxidants UNIROYAL INC. (US) 1977-06-21 US disclosed
US-3991016-A Poly(1,4-benzamide) copolymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-11-09 US disclosed
US-3951914-A Process for preparing poly(1,4-benzamide) in cyclic sulfone media E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-04-20 US disclosed
US-3931119-A AROMATIC CARBOXAMIDE-SULPHONAMIDE POLYCONDENSATES RHONE-POULENC S.A. (FR) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325711-A1 COVALENT FLUORESCENT PROBES FOR CANNABINOID RECEPTOR 2 CNR2, CNR1, QRFPR ALDH1A1 2396/4885HSD17B10 3488/4885TDP1 4169/4885
US-20260042806-A1 NOVEL PORE MONOMERS AND PORES SCNN1G, CACNG3, ASIC3 ALDH1A1 4800/4885HSD17B10 4856/4885TDP1 4238/4885
US-12366579-B2 Sulfur-heterocycle exchange chemistry and uses thereof TST, TPST2, SRMS ALDH1A1 3058/4885HSD17B10 4005/4885TDP1 1807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.