Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913341 | 0.87 | NPSR1 (0.67) | NPSR1TP53THRBENPP3KDR | |
| SCHEMBL7912137 | 0.80 | NPSR1 (0.56) | NPSR1TP53THRBENPP3KDR | |
| SCHEMBL7915171 | 0.78 | NPSR1 (0.61) | NPSR1THRBENPP3KDRMAPT | |
| SCHEMBL7914864 | 0.78 | NPSR1 (0.61) | NPSR1THRBENPP3KDRMAPT | |
| SCHEMBL7904915 | 0.76 | RXFP1 (0.57) | NPSR1TP53THRBKDRMAPT | |
| SCHEMBL7918550 | 0.76 | THRB (0.58) | NPSR1TP53THRBENPP3KDR | |
| SCHEMBL7913368 | 0.75 | MAPT (0.68) | NPSR1TP53THRBENPP3KDR | |
| SCHEMBL7914929 | 0.73 | MAPT (0.48) | NPSR1TP53THRBENPP3MAPT | |
| SCHEMBL1033861 | 0.73 | HPGD (0.53) | NPSR1TP53MAPTHTTHPGD | |
| SCHEMBL7912167 | 0.72 | MAPT (0.63) | NPSR1TP53THRBENPP3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |