Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16502621 | 0.88 | PLA2G2D (0.42) | — | |
| SCHEMBL16494630 | 0.85 | NQO2 (0.44) | PLAU | |
| SCHEMBL7919752 | 0.80 | HTR5A (0.48) | — | |
| SCHEMBL7916775 | 0.79 | PLAU (0.32) | PLAU | |
| SCHEMBL7916835 | 0.79 | PDE2A (0.35) | PLAU | |
| SCHEMBL7908906 | 0.75 | PLAU (0.34) | PLAU | |
| SCHEMBL7918472 | 0.75 | HSD17B14 (0.36) | PLAU | |
| SCHEMBL7920004 | 0.74 | PLAU (0.34) | PLAU | |
| SCHEMBL7915836 | 0.74 | GRM2 (0.35) | PLAUPDK2 | |
| SCHEMBL16494978 | 0.74 | NQO2 (0.45) | PLAUPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090304-A1 | ACYLGUANIDINE DERIVATIVE | アステラス製薬株式会社 (JP) | 2010-08-12 | — | — | WO | disclosed |