Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.35 |
| ▸ | ITGAV | P06756 | 9/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8187421 | 0.86 | ACHE (0.42) | — | |
| SCHEMBL7919341 | 0.85 | BRD4 (0.41) | ITGB3ITGA2BITGAVHTTGABRA1 | |
| SCHEMBL8467659 | 0.82 | GABRG2 (0.39) | ITGB3ITGA2BITGAVGABRA1GABRG2 | |
| SCHEMBL8525562 | 0.82 | ITGB3 (0.39) | ITGB3ITGA2BITGAVHTTTSHR | |
| SCHEMBL7910284 | 0.82 | ITGB3 (0.39) | ITGB3ITGA2BITGAVHTTTSHR | |
| SCHEMBL7919242 | 0.79 | TSHR (0.43) | ITGB3ITGA2BHTTSRD5A1TSHR | |
| SCHEMBL8503323 | 0.74 | ITGB3 (0.59) | ITGB3ITGA2BITGAV | |
| SCHEMBL7485250 | 0.71 | ITGB3 (0.38) | ITGB3ITGA2BHTT | |
| SCHEMBL7366878 | 0.70 | ITGB3 (0.38) | ITGB3ITGA2BITGAV | |
| SCHEMBL7672674 | 0.69 | ITGB3 (0.57) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225465-B1 | REACTING BENZOAZEPINE OR BENZODIAZEPINE DERIVATIVE WITH PROTECTED AMINE IN PRESENCE OF PALLADIUM CATALYST IN PRESENCE OF CARBON MONOXIDE, REMOVING PROTECTING GROUPS | SMITHKLINE BEECHAM PLC (GB) | 2001-05-01 | — | — | US | disclosed |