Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.37 |
| ▸ | AHCY | P23526 | 1/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HINT1 | P49773 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3624014 | 0.79 | ADORA2A (0.42) | ADORA2AADORA2BAHCYHINT1 | |
| SCHEMBL5505950 | 0.78 | AHCY (0.39) | ADORA2AADORA2BAHCYHINT1 | |
| SCHEMBL6465533 | 0.76 | AHCY (0.38) | ADORA2AADORA2BAHCYHINT1 | |
| SCHEMBL6829149 | 0.75 | AHCY (0.43) | ADORA2AADORA2BAHCYSLC29A1CDK1 | |
| SCHEMBL1696451 | 0.74 | ADORA3 (0.49) | ADORA2AADORA2BAHCYSLC29A1 | |
| SCHEMBL10709115 | 0.74 | ADORA2A (0.45) | ADORA2AADORA2BCYP2C19HINT1 | |
| SCHEMBL1938201 | 0.73 | AHCY (0.46) | ADORA2AADORA2BAHCYCDK1CCNB1 | |
| SCHEMBL6685951 | 0.73 | AHCY (0.46) | ADORA2AADORA2BAHCYCDK1CCNB1 | |
| SCHEMBL10707941 | 0.73 | ADORA2A (0.42) | ADORA2AADORA2BAHCYSLC29A1HINT1 | |
| SCHEMBL11012860 | 0.72 | HINT1 (0.39) | ADORA2AADORA2BCYP2C19HINT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242592-B1 | Process for the preparation of 2′-O-alkyl-guanosine, cytidine, and uridine phosphoramidites | ISIS PHARMACEUTICALS, INC. | 2001-06-05 | — | — | US | disclosed |