Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7920178 | 1.00 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3IDO1DGAT1 | |
| SCHEMBL6460852 | 0.90 | ALDH1A1 (0.38) | SLC6A4SLC6A2SLC6A3IDO1DGAT1 | |
| SCHEMBL6460854 | 0.90 | ALDH1A1 (0.38) | SLC6A4SLC6A2SLC6A3IDO1DGAT1 | |
| SCHEMBL6456957 | 0.88 | DRD2 (0.36) | SLC6A4SLC6A2SLC6A3IDO1DGAT1 | |
| SCHEMBL6456961 | 0.88 | DRD2 (0.36) | SLC6A4SLC6A2SLC6A3IDO1DGAT1 | |
| SCHEMBL6452592 | 0.87 | DRD2 (0.35) | SLC6A4SLC6A2SLC6A3IDO1DRD2 | |
| SCHEMBL6452587 | 0.87 | DRD2 (0.35) | SLC6A4SLC6A2SLC6A3IDO1DRD2 | |
| SCHEMBL11141599 | 0.87 | DRD2 (0.43) | SLC6A4IDO1DGAT1SOAT1DRD2 | |
| SCHEMBL11141596 | 0.87 | DRD2 (0.43) | SLC6A4IDO1DGAT1SOAT1DRD2 | |
| SCHEMBL6456705 | 0.86 | GAA (0.35) | SLC6A4SLC6A2SLC6A3IDO1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |