SCHEMBL7920528

SCHEMBL7920528

N#Cc1c(C(F)(F)F)ccc(F)c1Cl

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.42
KDM4E B2RXH2 5/20 0.41
ALDH1A1 P00352 5/20 0.41
GAA P10253 5/20 0.41
GLA P06280 4/20 0.41
HPGD P15428 4/20 0.41
HTT P42858 3/20 0.41
KMT2A Q03164 3/20 0.41
LMNA P02545 2/20 0.41
MEN1 O00255 2/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
AR P10275 9/20 0.38
MAPT P10636 2/20 0.36
SLC22A12 Q96S37 1/20 0.35
TP53 P04637 1/20 0.34
MAP2K1 Q02750 1/20 0.33
POLB P06746 1/20 0.33
TRPV4 Q9HBA0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7926453 0.82 NOTUM (0.42) KIF11KDM4EALDH1A1GAAGLA
SCHEMBL6706548 0.80 KIF11 (0.44) KIF11KDM4EALDH1A1GAAGLA
SCHEMBL4592838 0.79 ALDH1A1 (0.42) KDM4EALDH1A1HPGDKMT2AMEN1
SCHEMBL25983203 0.79 KIF11 (0.44) KIF11KDM4EALDH1A1GAAGLA
SCHEMBL29417016 0.77 KDM4E (0.39) KIF11KDM4EALDH1A1GAAGLA
SCHEMBL7920521 0.77 KDM4E (0.39) KIF11KDM4EALDH1A1GAAGLA
SCHEMBL7920588 0.77 KIF11 (0.42) KIF11KDM4EALDH1A1GAAGLA
SCHEMBL16555432 0.76 TRPV4 (0.43) KDM4EALDH1A1GAAGLAHPGD
SCHEMBL7555568 0.75 ALDH1A1 (0.39) KDM4EALDH1A1HPGDHTTKMT2A
SCHEMBL27414569 0.75 ALDH1A1 (0.46) KDM4EALDH1A1GAAGLAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0847977-B1 2,3-DIHALOGENO-6-TRIFLUOROMETHYLBENZENE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME NIPPON SODA CO (JP) 2001-08-29 EP claimed
EP-0847977-A1 2,3-DIHALOGENO-6-TRIFLUOROMETHYLBENZENE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME NIPPON SODA CO., LTD. (JP) 1998-06-17 EP claimed
EP-0847977-B1 2,3-DIHALOGENO-6-TRIFLUOROMETHYLBENZENE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME NIPPON SODA CO (JP) 2001-08-29 EP disclosed
US-6054605-A CHEMICAL INTERMEDIATE FOR DRUGS, PESTICIDES NIPPON SODA CO., LTD. (JP) 2000-04-25 US disclosed
US-6054624-A USEFUL AS THE STARTING MATERIALS FOR PRODUCING PESTICIDES, DRUGS AND THE LIKE NIPPON SODA CO., LTD. (JP) 2000-04-25 US disclosed
EP-0847977-A1 2,3-DIHALOGENO-6-TRIFLUOROMETHYLBENZENE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME NIPPON SODA CO., LTD. (JP) 1998-06-17 EP disclosed