SCHEMBL6706548

SCHEMBL6706548

N#Cc1c(C(F)(F)F)ccc(F)c1F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.44
ALDH1A1 P00352 9/20 0.37
KDM4E B2RXH2 9/20 0.37
GAA P10253 8/20 0.37
HTT P42858 3/20 0.37
KMT2A Q03164 2/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 7/20 0.36
GLA P06280 6/20 0.36
LMNA P02545 3/20 0.36
MEN1 O00255 1/20 0.36
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
TP53 P04637 1/20 0.36
TRPV4 Q9HBA0 1/20 0.34
AR P10275 5/20 0.34
PGR P06401 1/20 0.34
ATM Q13315 1/20 0.33
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25983203 0.82 KIF11 (0.44) KIF11ALDH1A1KDM4EGAAHTT
SCHEMBL29417016 0.80 KDM4E (0.39) KIF11ALDH1A1KDM4EGAAHTT
SCHEMBL7920528 0.80 KIF11 (0.42) KIF11ALDH1A1KDM4EGAAHTT
SCHEMBL5109158 0.80 KIF11 (0.39) KIF11ALDH1A1KDM4EGAAHTT
SCHEMBL7920588 0.80 KIF11 (0.42) KIF11ALDH1A1KDM4EGAAHTT
SCHEMBL7920521 0.80 KDM4E (0.39) KIF11ALDH1A1KDM4EGAAHTT
SCHEMBL186689 0.77 TRPV4 (0.42) ALDH1A1KDM4EGAAKMT2AMAPT
SCHEMBL25991351 0.75 KIF11 (0.41) KIF11ALDH1A1KDM4EGAAHTT
SCHEMBL646513 0.75 L3MBTL1 (0.44) KIF11ALDH1A1KDM4EGAAHTT
SCHEMBL7625945 0.74 AR (0.40) KIF11ALDH1A1KDM4EGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116283661-B 2, 3-Difluoro-6- (trifluoromethyl) -benzonitrile compound and preparation method thereof 江苏广域化学有限公司 2025-05-09 CN claimed
CN-116283661-A 2, 3-difluoro-6- (trifluoromethyl) -benzonitrile compound and preparation method thereof 江苏广域化学有限公司 2023-06-23 CN claimed
EP-0847977-B1 2,3-DIHALOGENO-6-TRIFLUOROMETHYLBENZENE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME NIPPON SODA CO (JP) 2001-08-29 EP claimed
US-6211232-B1 REACTION OF BENZONITRILE WITH HYDROXYLAMINE IN THE PRESENCE OF CHELATION AGENT NIPPON SODA CO., LTD. (JP) 2001-04-03 US claimed
EP-1061068-A1 PROCESS FOR PRODUCING BENZAMIDOXIMES NIPPON SODA CO., LTD. (JP) 2000-12-20 EP claimed
EP-0847977-A1 2,3-DIHALOGENO-6-TRIFLUOROMETHYLBENZENE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME NIPPON SODA CO., LTD. (JP) 1998-06-17 EP claimed
JP-10168051-A None JP disclosed
JP-11255733-A None JP disclosed
CN-122079736-A Method for preparing 6-bromo-2, 3-difluoro benzotrifluoride 2026-05-26 CN disclosed
CN-116283661-B 2, 3-Difluoro-6- (trifluoromethyl) -benzonitrile compound and preparation method thereof 江苏广域化学有限公司 2025-05-09 CN disclosed
CN-116283661-B 2, 3-Difluoro-6- (trifluoromethyl) -benzonitrile compound and preparation method thereof 江苏广域化学有限公司 2025-05-09 CN disclosed
CN-116283661-B 2, 3-Difluoro-6- (trifluoromethyl) -benzonitrile compound and preparation method thereof 江苏广域化学有限公司 2025-05-09 CN disclosed
CN-116283661-A 2, 3-difluoro-6- (trifluoromethyl) -benzonitrile compound and preparation method thereof 江苏广域化学有限公司 2023-06-23 CN disclosed
US-6054605-A CHEMICAL INTERMEDIATE FOR DRUGS, PESTICIDES NIPPON SODA CO., LTD. (JP) 2000-04-25 US disclosed
US-6054624-A USEFUL AS THE STARTING MATERIALS FOR PRODUCING PESTICIDES, DRUGS AND THE LIKE NIPPON SODA CO., LTD. (JP) 2000-04-25 US disclosed
US-5977414-A 2,3-Dihalogeno-6-trifluoromethylbenzene derivatives and processes for the preparation thereof NIPPON SODA CO., LTD. (JP) 1999-11-02 US disclosed
JP-H11255733-A PRODUCTION OF BENZAMIDOXIMES NIPPON SODA CO LTD 1999-09-21 JP disclosed
EP-0881207-A1 2,3-DIHALOGENO-6-TRIFLUOROMETHYLBENZENE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF NIPPON SODA CO., LTD. (JP) 1998-12-02 EP disclosed
JP-H10168051-A PRODUCTION OF 2,3-DIHALOGENO-6-TRIFLUOROMETHYLBENZONITRILE NIPPON SODA CO LTD 1998-06-23 JP disclosed
EP-0847977-A1 2,3-DIHALOGENO-6-TRIFLUOROMETHYLBENZENE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME NIPPON SODA CO., LTD. (JP) 1998-06-17 EP disclosed