Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TK2 | O00142 | 1/20 | 0.37 |
| ▸ | TK1 | P04183 | 1/20 | 0.37 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7928080 | 0.87 | LMNA (0.37) | TK2TK1 | |
| SCHEMBL7926896 | 0.79 | RNASE1 (0.41) | MEN1KMT2ARXFP1RNASE1 | |
| SCHEMBL7929690 | 0.69 | LMNA (0.41) | TK2TK1 | |
| SCHEMBL8625601 | 0.68 | LMNA (0.46) | RXFP1TK2TK1 | |
| SCHEMBL5982320 | 0.68 | TK1 (0.65) | TK2TK1 | |
| SCHEMBL21115874 | 0.68 | TK1 (0.65) | TK2TK1 | |
| SCHEMBL22560281 | 0.68 | TK1 (0.65) | TK2TK1 | |
| SCHEMBL21115872 | 0.68 | TK1 (0.65) | TK2TK1 | |
| SCHEMBL21071421 | 0.68 | TK1 (0.65) | TK2TK1 | |
| SCHEMBL5982324 | 0.68 | TK1 (0.65) | TK2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239159-B1 | SUBSTRATES FOR POLYMERASE AND TERMINAL TRANSFERASE ENZYMES. CAPABLE OF BASE-PAIRING WITH A NUCLEOTIDE RESIDUE IN A COMPLEMENTARY CHAIN OR BASE STACKING IN THE APPROPRIATE NUCLEIC ACID CHAIN, ADVANTAGE OVER CONVENTIONAL HAPTEN | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 2001-05-29 | — | — | US | disclosed |