Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | TK1 | P04183 | 3/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | TK2 | O00142 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921052 | 0.87 | MEN1 (0.40) | TK1TK2 | |
| SCHEMBL7929690 | 0.81 | LMNA (0.41) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL8625601 | 0.80 | LMNA (0.46) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL9253854 | 0.66 | TK1 (0.66) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL9253844 | 0.66 | TK1 (0.66) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL149648 | 0.66 | ADRB1 (0.50) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL2193016 | 0.66 | ADRB1 (0.50) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL5983020 | 0.66 | TK1 (0.69) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL15285228 | 0.66 | TK1 (0.69) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL5983012 | 0.66 | TK1 (0.69) | LMNASMN1; SMN2ALOX12ADRA1ATK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239159-B1 | SUBSTRATES FOR POLYMERASE AND TERMINAL TRANSFERASE ENZYMES. CAPABLE OF BASE-PAIRING WITH A NUCLEOTIDE RESIDUE IN A COMPLEMENTARY CHAIN OR BASE STACKING IN THE APPROPRIATE NUCLEIC ACID CHAIN, ADVANTAGE OVER CONVENTIONAL HAPTEN | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 2001-05-29 | — | — | US | disclosed |