Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 2/20 | 0.33 |
| ▸ | FNTB | P49356 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908229 | 0.92 | PTPN11 (0.35) | FNTAFNTBLTB4R2FAAH | |
| SCHEMBL7918553 | 0.76 | SLC6A4 (0.41) | SLC6A4SLC6A3FNTAFNTBALDH1A1 | |
| SCHEMBL7871095 | 0.74 | LTB4R2 (0.38) | LTB4R2FAAH | |
| SCHEMBL7907018 | 0.71 | FNTA (0.41) | FNTAFNTB | |
| SCHEMBL7904963 | 0.71 | SLC6A4 (0.37) | SLC6A4SLC6A3FNTAFNTBLTB4R2 | |
| SCHEMBL7921366 | 0.70 | LTB4R2 (0.38) | SLC6A4SLC6A3FNTAFNTBLTB4R2 | |
| SCHEMBL6627724 | 0.69 | HTR1A (0.51) | FNTAFNTBLTB4R2BDKRB1 | |
| SCHEMBL7867462 | 0.67 | FNTA (0.39) | FNTAFNTB | |
| SCHEMBL10193055 | 0.66 | LTB4R2 (0.39) | LTB4R2BDKRB1 | |
| SCHEMBL7867498 | 0.66 | LTB4R2 (0.36) | LTB4R2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221865-B1 | INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE. | UNIVERSITY OF PITTSBURGH | 2001-04-24 | — | — | US | disclosed |