Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 7/20 | 0.56 |
| ▸ | CES1 | P23141 | 7/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14278529 | 0.87 | CES2 (0.53) | CES2CES1TDP1L3MBTL1KMT2A | |
| SCHEMBL15969657 | 0.85 | CES2 (0.49) | CES2CES1TDP1L3MBTL1KMT2A | |
| SCHEMBL15969246 | 0.83 | L3MBTL1 (0.51) | CES2CES1TDP1L3MBTL1KMT2A | |
| SCHEMBL11963937 | 0.83 | L3MBTL1 (0.51) | CES2CES1TDP1L3MBTL1KMT2A | |
| SCHEMBL13538631 | 0.77 | ALDH1A1 (0.53) | CES2CES1L3MBTL1KMT2ARAB9A | |
| SCHEMBL10903680 | 0.75 | HDAC3 (0.47) | CES2CES1TDP1L3MBTL1KMT2A | |
| Benzoyl Formic Acid SCHEMBL23498287 | 0.75 | CES2 (0.58) | CES2CES1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL1348555 | 0.74 | NPC1 (0.54) | CES2CES1L3MBTL1KMT2ARAB9A | |
| SCHEMBL11963958 | 0.74 | KMT2A (0.58) | CES2CES1TDP1L3MBTL1KMT2A | |
| SCHEMBL12511943 | 0.74 | L3MBTL1 (0.56) | TDP1L3MBTL1KMT2ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200831-B1 | HEAT-CURING A COATING OF A POLYAMIC ACID BASED ON A TETRACARBOXYLIC ACID AND A DIAMINE CONTAINNG AN ACTIVE OXYGEN OR NITROGEN FUNCTIONAL GROUP; SEALING THE EXTERNAL TERMINALS WITH A RESIN, E.G. AN EPOXIDE | HITACHI, LTD. (JP) | 2001-03-13 | — | — | US | disclosed |