Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | DBH | P09172 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSSK1B | Q9BXA7 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049079 | 0.83 | ENPP2 (0.50) | KDM4EDBHGAARECQL | |
| SCHEMBL10121174 | 0.82 | KDM4E (0.62) | KDM4EDBHGAARECQLLMNA | |
| SCHEMBL10136469 | 0.82 | CA2 (0.59) | KDM4EDBHGAARECQLCA2 | |
| SCHEMBL16473924 | 0.82 | KDM4E (0.46) | KDM4EDBHGAARECQLALDH1A1 | |
| SCHEMBL22623462 | 0.81 | ALDH1A1 (0.47) | KDM4EDBHGAARECQLLMNA | |
| SCHEMBL15045392 | 0.79 | SMN1; SMN2 (0.52) | KDM4EDBHGAARECQLLMNA | |
| SCHEMBL601340 | 0.76 | ALDH1A1 (0.58) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL7646230 | 0.76 | ALDH1A1 (0.58) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL10941943 | 0.75 | KDM4E (0.56) | KDM4EDBHGAARECQLLMNA | |
| SCHEMBL12418688 | 0.75 | KDM4E (0.56) | KDM4EDBHGAARECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6229022-B1 | REACTING CARBONYL COMPOUNDS WITH HYDRAZINE, ITS HYDRATE OR SALTS IN THE PRESENCE OF SULFURIC ACID AND IODINE OR AN IODINE LIBERATING COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-08 | — | — | US | disclosed |