Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 7/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7919718 | 0.76 | POLB (0.32) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7919786 | 0.74 | DHODH (0.36) | LMNAALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL7919364 | 0.73 | MEN1 (0.46) | THRBALDH1A1SMN1; SMN2PTGS2 | |
| SCHEMBL7922604 | 0.71 | GAA (0.40) | LMNANPSR1 | |
| SCHEMBL11832550 | 0.68 | NTRK1 (0.39) | THRBNPBWR1MCHR1SMN1; SMN2 | |
| SCHEMBL7910299 | 0.68 | ALDH1A1 (0.33) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7922620 | 0.68 | MEN1 (0.53) | LMNAALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL11716855 | 0.64 | ALDH1A1 (0.39) | THRBLMNAALDH1A1NPBWR1MCHR1 | |
| SCHEMBL9504425 | 0.64 | NPBWR1 (0.35) | LMNAALDH1A1NPBWR1MCHR1SMN1; SMN2 | |
| SCHEMBL9502409 | 0.63 | THRB (0.44) | THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211178-B1 | ANTIPROTOZOA AGENTS FOR COCCIDIOIDES; CYCLIZATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0648760-B1 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-01-27 | — | — | EP | disclosed |
| EP-0648760-A2 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |