Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10501484 | 0.85 | THRB (0.43) | THRBSLC6A4ALDH1A1CYP3A4TSHR | |
| SCHEMBL9504425 | 0.84 | NPBWR1 (0.35) | SLC6A4ALDH1A1SLC6A2SLC6A3 | |
| SCHEMBL9501110 | 0.77 | PTGS2 (0.39) | — | |
| SCHEMBL9501834 | 0.77 | LMNA (0.32) | THRB | |
| SCHEMBL9500876 | 0.77 | THRB (0.38) | THRBSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11713543 | 0.75 | THRB (0.44) | THRBSLC6A4ALDH1A1CYP3A4TSHR | |
| SCHEMBL10501699 | 0.72 | SLC6A4 (0.40) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL9502425 | 0.72 | THRB (0.82) | THRB | |
| SCHEMBL11453921 | 0.71 | ALDH1A1 (0.43) | THRBSLC6A4ALDH1A1CYP3A4TSHR | |
| SCHEMBL9501160 | 0.69 | LMNA (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154885-B1 | SUBSTITUTED 2-PHENYL-HEXAHYDRO-1,2,4-TRIAZINE-2,5-DIONES, METHOD FOR THEIR PREPARATION, THEIR USE AS VETERINARY MEDICINES AND FOR COMBATING PROTOZOES | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-18 | — | — | EP | claimed |
| US-5188832-A | Triazine-dione compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-23 | — | — | US | disclosed |
| EP-0383285-A2 | Agent against fish and insect parasites | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-22 | — | — | EP | disclosed |
| EP-0154885-B1 | SUBSTITUTED 2-PHENYL-HEXAHYDRO-1,2,4-TRIAZINE-2,5-DIONES, METHOD FOR THEIR PREPARATION, THEIR USE AS VETERINARY MEDICINES AND FOR COMBATING PROTOZOES | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-18 | — | — | EP | disclosed |
| US-4640917-A | 2-phenyl-hexahydro-1,2,4-triazine-3,5-diones | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-02-03 | — | — | US | disclosed |
| EP-0154885-A1 | Substituted 2-phenyl-hexahydro-1,2,4-triazine-2,5-diones, method for their preparation, their use as veterinary medicines and for combating protozoes | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-09-18 | — | — | EP | disclosed |