Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812840 | 0.87 | LMNA (0.52) | LMNAPOLBALDH1A1TSHRSMN1; SMN2 | |
| Barium SCHEMBL2592652 | 0.85 | LMNA (0.50) | LMNAPOLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL16345225 | 0.85 | LMNA (0.50) | LMNAPOLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL3757540 | 0.85 | LMNA (0.50) | LMNAPOLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL3353998 | 0.82 | ALDH1A1 (0.62) | LMNAPOLBALDH1A1TSHRSMN1; SMN2 | |
| Alcohol SCHEMBL7527792 | 0.82 | LMNA (0.49) | LMNAPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL594011 | 0.81 | TSHR (0.54) | LMNAPOLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6975491 | 0.81 | TSHR (0.46) | LMNAPOLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL247203 | 0.79 | — | — | |
| Ethylene Glycol SCHEMBL11791402 | 0.79 | LMNA (0.50) | LMNAPOLBALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6231783-B1 | SOLVENT SYSTEMS HAVING IMPROVED PHYSICAL PROPERTIES TO MINIMIZE ENTRY INTO THE ENVIRONMENT AND TO FACILITATE SEPARATIONS AND CLEANING OPERATIONS TO MINIMIZE POLLUTION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2001-05-15 | — | — | US | disclosed |
| WO-1997018179-A1 | REPLACEMENT SOLVENTS FOR USE IN CHEMICAL SYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1997-05-22 | — | — | WO | disclosed |