SCHEMBL7922755

SCHEMBL7922755

CC(C)Cc1cccc(OCCOCCc2ccccc2C(C)(C)N)c1CC(C)C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
LMNA P02545 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
HSP90AB1 P08238 3/20 0.33
GAA P10253 2/20 0.32
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPK1 P28482 1/20 0.32
ADRB2 P07550 2/20 0.32
ADRB1 P08588 2/20 0.32
MAPT P10636 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
L3MBTL1 Q9Y468 3/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
NCF1 P14598 2/20 0.30
DRD2 P14416 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11559574 0.78 ALOX15 (0.37) HTTTDP1LMNANPSR1KDM4E
Hydrochloric Acid SCHEMBL10494208 0.75 GABRA1 (0.34) KMT2AGABRA1GABRB2
SCHEMBL7928465 0.74 ALDH1A1 (0.42) HTTTDP1NPSR1GAAKDM4E
SCHEMBL9805596 0.74 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL9179948 0.74 ADRB2 (0.34) KDM4EALDH1A1ADRB2ADRB1MEN1
Hydrochloric Acid SCHEMBL9398193 0.73 GABRA1 (0.35) LMNANPSR1KDM4EALDH1A1MAPK1
Hydrochloric Acid SCHEMBL423996 0.73 GABRA1 (0.33) GABRA1GABRB2
Hydrochloric Acid SCHEMBL5438428 0.73 ADRB2 (0.33) ADRB2ADRB1DRD2HTR2AHTR7
Hydrochloric Acid SCHEMBL4850065 0.72 GABRA1 (0.32) KMT2AGABRA1GABRB2
SCHEMBL3387763 0.70 GABRA1 (0.31) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111246739-B Quaternary ammonium salt of hydroxyethylphosphonic acid 创新水护理有限责任公司 2021-07-27 CN disclosed
CN-111246739-A Quaternary ammonium salt of hydroxyethylphosphonic acid 创新水护理有限责任公司 2020-06-05 CN disclosed
US-6225260-B1 USE OF SUCH COMPOUNDS AS PESTICIDES, HERBICIDES, FUNGICIDES, AND PLANT GROWTH REGULATING AGENTS. LONZA INC. 2001-05-01 US disclosed