SCHEMBL7928465

SCHEMBL7928465

CC(C)Cc1cccc(OCCOCCNC(C)(C)c2ccccc2)c1CC(C)C

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
KDM4E B2RXH2 10/20 0.38
GAA P10253 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
NCF1 P14598 2/20 0.34
ADRB2 P07550 3/20 0.34
ADRB1 P08588 2/20 0.34
NPSR1 Q6W5P4 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HTR1A P08908 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7922755 0.74 HTT (0.35) ALDH1A1KDM4EGAAMAPK1HTT
SCHEMBL1013751 0.74 GABRA1 (0.34)
SCHEMBL9324541 0.74 KDM4E (0.50) ALDH1A1KDM4EHTTTDP1MEN1
Hydrochloric Acid SCHEMBL512162 0.73 GABRA1 (0.33)
Hydrochloric Acid SCHEMBL9398193 0.72 GABRA1 (0.35) ALDH1A1KDM4EMAPK1NCF1ADRB2
Hydrochloric Acid SCHEMBL7785893 0.71 KMT2A (0.48) ALDH1A1MAPK1HTTTDP1MEN1
SCHEMBL25267340 0.70 GABRA1 (0.31)
Water SCHEMBL11423879 0.70 KMT2A (0.48) ALDH1A1MAPK1HTTTDP1MEN1
Hydrochloric Acid SCHEMBL1858922 0.70 GABRA1 (0.31)
Hydrochloric Acid SCHEMBL11607442 0.69 GABRA1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6225260-B1 USE OF SUCH COMPOUNDS AS PESTICIDES, HERBICIDES, FUNGICIDES, AND PLANT GROWTH REGULATING AGENTS. LONZA INC. 2001-05-01 US claimed
US-10793586-B2 Quaternary ammonium etidronates INNOVATIVE WATER CARE, LLC (US) 2020-10-06 US disclosed
EP-3691450-A1 QUATERNARY AMMONIUM ETIDRONATES Innovative Water Care, LLC (US) 2020-08-12 EP disclosed
US-20190106445-A1 QUATERNARY AMMONIUM ETIDRONATES THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., AS NOTES COLLATERAL AGENT 2019-04-11 US disclosed
WO-2019071070-A1 QUATERNARY AMMONIUM ETIDRONATES ARCH CHEMICALS, INC. (US) 2019-04-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10793586-B2 Quaternary ammonium etidronates POLR1C, QARS1, ATP6V1E1 ALDH1A1 2381/4885KDM4E 440/4885GAA 167/4885
US-20190106445-A1 QUATERNARY AMMONIUM ETIDRONATES POLR1C, QARS1, ATP6V1E1 ALDH1A1 2381/4885KDM4E 440/4885GAA 167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.