Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.39 |
| ▸ | ACHE | P22303 | 7/20 | 0.39 |
| ▸ | BCHE | P06276 | 6/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929312 | 0.84 | PTGS2 (0.41) | PTGS2ACHEBCHE | |
| SCHEMBL7932743 | 0.81 | PPARA (0.34) | — | |
| SCHEMBL7932749 | 0.77 | PTGER1 (0.30) | PTGER1PTGER3PTGER2 | |
| SCHEMBL7932741 | 0.77 | PTGER1 (0.30) | PTGER1PTGER3PTGER2 | |
| SCHEMBL7930959 | 0.76 | RARB (0.39) | PTGS2ACHEBCHE | |
| SCHEMBL8176887 | 0.75 | PTPRC (0.35) | PTGS2ACHEBCHERAB9A | |
| SCHEMBL1376557 | 0.75 | CHRNB2 (0.41) | PTGS2ACHEBCHE | |
| SCHEMBL7929362 | 0.72 | FYN (0.38) | ACHEBACE1 | |
| SCHEMBL7929366 | 0.72 | FYN (0.38) | ACHEBACE1 | |
| SCHEMBL5704661 | 0.71 | L3MBTL1 (0.41) | PTGS2ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879814-B1 | Triaromatic compounds, compositions containing them and uses thereof | CT INTERNAT DE BR RECH S DERMA (FR) | 2001-11-28 | — | — | EP | disclosed |
| US-6150413-A | TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, BONE AND OPHTHALMOLOGICAL DISORDERS, AS WELL AS MAMMALIAN SKIN AND HAIR CONDITIONS; 4-(4-(BIPHENYL-2-YL)BUT-3-EN-1-YNYL)BENZOIC ACID, FOR EXAMPLE | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2000-11-21 | — | — | US | disclosed |
| EP-0879814-A1 | Triaromatic compounds, compositions containing them and uses thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-11-25 | — | — | EP | disclosed |