Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 8/20 | 0.38 |
| ▸ | BCHE | P06276 | 6/20 | 0.38 |
| ▸ | ERN1 | O75460 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922792 | 0.84 | PTGS2 (0.39) | PTGS2ACHEBCHE | |
| SCHEMBL7922729 | 0.80 | XDH (0.38) | XDHERN1 | |
| SCHEMBL1376557 | 0.77 | CHRNB2 (0.41) | PTGS2ACHEBCHE | |
| SCHEMBL7922724 | 0.76 | XDH (0.37) | PTGS2XDHERN1ALDH1A1LMNA | |
| SCHEMBL2047680 | 0.76 | PTGS2 (0.53) | PTGS2ACHEBCHEALDH1A1 | |
| SCHEMBL5937063 | 0.74 | TYR (0.48) | XDHERN1ALDH1A1LMNA | |
| SCHEMBL28009606 | 0.73 | ERN1 (0.49) | XDHERN1ALDH1A1LMNA | |
| SCHEMBL5704661 | 0.73 | L3MBTL1 (0.41) | PTGS2ACHEBCHELMNACYP1A2 | |
| SCHEMBL11768743 | 0.73 | LMNA (0.60) | XDHERN1ALDH1A1LMNA | |
| SCHEMBL30497064 | 0.73 | LMNA (0.60) | XDHERN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879814-B1 | Triaromatic compounds, compositions containing them and uses thereof | CT INTERNAT DE BR RECH S DERMA (FR) | 2001-11-28 | — | — | EP | disclosed |
| US-6150413-A | TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, BONE AND OPHTHALMOLOGICAL DISORDERS, AS WELL AS MAMMALIAN SKIN AND HAIR CONDITIONS; 4-(4-(BIPHENYL-2-YL)BUT-3-EN-1-YNYL)BENZOIC ACID, FOR EXAMPLE | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2000-11-21 | — | — | US | disclosed |
| EP-0879814-A1 | Triaromatic compounds, compositions containing them and uses thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-11-25 | — | — | EP | disclosed |