Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22311218 | 0.90 | PTGS2 (0.46) | CHRNB2CHRNA4PTGS2BCHEACHE | |
| SCHEMBL5704661 | 0.88 | L3MBTL1 (0.41) | PTGS2BCHEACHEL3MBTL1 | |
| SCHEMBL2522160 | 0.84 | PTGS2 (0.47) | CHRNB2CHRNA4PTGS2EPHX1MMP12 | |
| SCHEMBL1372415 | 0.79 | ACHE (0.42) | PTGS2BCHEACHE | |
| SCHEMBL27191 | 0.78 | ACHE (0.47) | PTGS2BCHEACHEL3MBTL1 | |
| SCHEMBL7929312 | 0.77 | PTGS2 (0.41) | PTGS2BCHEACHE | |
| SCHEMBL28346107 | 0.77 | CHRNB2 (0.44) | CHRNB2CHRNA4PTGS2L3MBTL1CYP17A1 | |
| SCHEMBL29222878 | 0.77 | PTGS2 (0.46) | CHRNB2CHRNA4PTGS2L3MBTL1 | |
| SCHEMBL19543236 | 0.76 | NQO1 (0.54) | PTGS2BCHEACHEL3MBTL1 | |
| SCHEMBL7922792 | 0.75 | PTGS2 (0.39) | PTGS2BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110287549-A1 | TIME TEMPERATURE INDICATOR BASED ON THIOALKYL AND THIOARYL SUBSTITUTED SPIROAROMATICS | FRESHPOINT HOLDINGS SA (CH) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287549-A1 | TIME TEMPERATURE INDICATOR BASED ON THIOALKYL AND THIOARYL SUBSTITUTED SPIROAROMATICS | TPI1, TTI1, TST | CHRNB2 4839/4885CHRNA4 4833/4885PTGS2 375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.