Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 2/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.31 |
| ▸ | FPR3 | P25089 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917158 | 0.76 | MTNR1A (0.50) | ATM | |
| SCHEMBL7921878 | 0.75 | EPHX1 (0.44) | KMT2AMITF | |
| SCHEMBL7915722 | 0.72 | MTNR1A (0.48) | KMT2AATMMITF | |
| SCHEMBL14040657 | 0.68 | MC4R (0.41) | KMT2AATMMITF | |
| SCHEMBL7910450 | 0.68 | ATM (0.61) | KMT2AATMFPR3FPR2 | |
| SCHEMBL13281154 | 0.67 | GABRA5 (0.35) | KMT2A | |
| SCHEMBL7922905 | 0.64 | MME (0.48) | ATMSMYD3 | |
| SCHEMBL7918857 | 0.63 | ATM (0.59) | KMT2AATMMITF | |
| SCHEMBL25221309 | 0.63 | EPHX1 (0.42) | SMYD3 | |
| SCHEMBL14040646 | 0.63 | MC4R (0.42) | KMT2AATMMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010054968-A1 | QUINAZOLINE DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-05-20 | — | — | WO | disclosed |