Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TRIP13 | Q15645 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825002 | 0.81 | ALDH1A1 (0.56) | MGLLALDH1A1LMNAPOLBHSP90AA1 | |
| SCHEMBL11283819 | 0.80 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNAPOLBMAPT | |
| SCHEMBL9638467 | 0.79 | FAAH (0.47) | FAAHMGLLALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL16681934 | 0.79 | ALDH1A1 (0.47) | FAAHMGLLALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL20846699 | 0.77 | ALDH1A1 (0.59) | ALDH1A1LMNAPOLBMAPTMEN1 | |
| SCHEMBL14069644 | 0.76 | MGLL (0.61) | FAAHMGLLALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL16675655 | 0.76 | GAA (0.48) | FAAHMGLLALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7930127 | 0.75 | ALDH1A1 (0.50) | FAAHMGLLALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL14159540 | 0.73 | MGLL (0.62) | FAAHMGLLALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11755589 | 0.73 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2POLBHSP90AA1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800551-B1 | SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS | AKZO NOBEL NV (NL) | 2001-06-13 | — | — | EP | disclosed |
| US-5844049-A | Sulfur-vulcanized rubber compositions comprising substituted succinimide compounds | AKZO NOBEL NV (NL) | 1998-12-01 | — | — | US | disclosed |
| EP-0800551-A1 | SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS | Akzo Nobel N.V. (NL) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996020246-A1 | SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS | AKZO NOBEL N.V. (NL) | 1996-07-04 | — | — | WO | disclosed |